Tschubel K, Helpap B
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1975 Nov 25;84(3):271-9. doi: 10.1007/BF00312248.
250 tissue biopsies of the mamma were examined simultaneously by intraoperative histology (frozen sections) and imprint cytology. In 95% of the cases there was a good agreement between the histologic and cytologic diagnoses. The reliability of the imprint cytology was tested in some complicated cases such as proliferating fibroadenomas, sclerosing adenosis and carcinomas and the significance of the imprint cytology for the diagnosis of difficult cases was pointed out in detail. The results have demonstrated, that such a cytologic examination can not be a substitute for intraoperative frozen sections - but the simultaneous cytologic examination of unfixed mamma biopsies can be a good searching method and can be helpful in the intraoperative diagnostic.
对250份乳腺组织活检标本同时进行术中组织学检查(冰冻切片)和印片细胞学检查。在95%的病例中,组织学诊断和细胞学诊断结果吻合良好。在一些复杂病例(如增生性纤维腺瘤、硬化性腺病和癌)中对印片细胞学的可靠性进行了检测,并详细指出了印片细胞学在疑难病例诊断中的意义。结果表明,这种细胞学检查不能替代术中冰冻切片——但对未固定的乳腺活检标本同时进行细胞学检查可以作为一种很好的筛查方法,有助于术中诊断。