Liao Susan, Li Bojun, Ma Zuwei, Wei He, Chan Casey, Ramakrishna Seeram
Nanoscience and Nanotechnology Initiative (NUSNNI), Faculty of Engineering, National University of Singapore, 117576 Singapore.
Biomed Mater. 2006 Sep;1(3):R45-53. doi: 10.1088/1748-6041/1/3/R01. Epub 2006 Jul 28.
Nanofibers exist widely in human tissue with different patterns. Electrospinning nanotechnology has recently gained a new impetus due to the introduction of the concept of biomimetic nanofibers for tissue regeneration. The advanced electrospinning technique is a promising method to fabricate a controllable continuous nanofiber scaffold similar to the natural extracellular matrix. Thus, the biomedical field has become a significant possible application field of electrospun fibers. Although electrospinning has developed rapidly over the past few years, electrospun nanofibers are still at a premature research stage. Further comprehensive and deep studies on electrospun nanofibers are essential for promoting their biomedical applications. Current electrospun fiber materials include natural polymers, synthetic polymers and inorganic substances. This review briefly describes several typically electrospun nanofiber materials or composites that have great potential for tissue regeneration, and describes their fabrication, advantages, drawbacks and future prospects.
纳米纤维以不同模式广泛存在于人体组织中。由于引入了用于组织再生的仿生纳米纤维概念，静电纺丝纳米技术最近获得了新的推动力。先进的静电纺丝技术是制造类似于天然细胞外基质的可控连续纳米纤维支架的一种有前途的方法。因此，生物医学领域已成为静电纺丝纤维一个重要的潜在应用领域。尽管在过去几年中静电纺丝发展迅速，但电纺纳米纤维仍处于研究初期阶段。对电纺纳米纤维进行进一步全面深入的研究对于促进其生物医学应用至关重要。目前的电纺纤维材料包括天然聚合物、合成聚合物和无机物。本文综述简要描述了几种在组织再生方面具有巨大潜力的典型电纺纳米纤维材料或复合材料，并介绍了它们的制备方法、优点、缺点和未来前景。
