Xu Hong, Wang Yingjun, Zheng Yudong, Chen Xiaofeng, Ren Li, Wu Gang, Huang Xiaoshan
College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, People's Republic of China.
Biomed Mater. 2007 Jun;2(2):62-6. doi: 10.1088/1748-6041/2/2/002. Epub 2007 Mar 7.
In order to form firm active fixation with the adjacent bone, a new kind of bioactive composite hydrogel was prepared with polyvinyl alcohol (PVA) and bioglass (BG) through ultrasonic dispersion, heat-high-pressure and freeze/thawed technique. A digital speckle correlation method (DSCM) was utilized to characterize the mechanical properties of the series of BG/PVA composites. Results showed that at different load pressures, the composite hydrogel displayed different displacement and deformation in the V field. Results also showed that an increase of PVA percentage (15-30 wt%) or of bioglass percentage (2-10 wt%) in composite hydrogel could lead to an increase in the elastic compression modulus. Scanning electron microscope results indicated that bioglass was uniformly dispersed in the BG/PVA composite hydrogel. The BG/PVA composite hydrogel shows a promising prospect as a new bionic cartilage implantation material.
为了与相邻骨骼形成牢固的主动固定，通过超声分散、热高压和冻融技术，用聚乙烯醇（PVA）和生物玻璃（BG）制备了一种新型生物活性复合水凝胶。利用数字散斑相关方法（DSCM）表征了一系列BG/PVA复合材料的力学性能。结果表明，在不同的负载压力下，复合水凝胶在V场中表现出不同的位移和变形。结果还表明，复合水凝胶中PVA百分比（15 - 30 wt%）或生物玻璃百分比（2 - 10 wt%）的增加会导致弹性压缩模量的增加。扫描电子显微镜结果表明，生物玻璃均匀分散在BG/PVA复合水凝胶中。BG/PVA复合水凝胶作为一种新型的仿生软骨植入材料具有广阔的应用前景。
