Cassart M, Bosson N, Garel C, Eurin D, Avni F
Department of Medical Imaging, Erasme University Hospital, 808 Route de Lennik, 1070 Brussels, Belgium.
Eur Radiol. 2008 Oct;18(10):2060-6. doi: 10.1007/s00330-008-0999-5. Epub 2008 May 6.
Fetal intracranial tumors are rare. The diagnosis is generally made on histology after birth. The aim of this study was to analyze clinical and imaging data in a series of fetal intracranial tumors and emphasize the findings that may help approach the diagnosis antenatally. We retrospectively analyzed imaging and clinical findings in 27 cases of fetal intracranial tumors assessed by ultrasound (27/27) and MR imaging (24/27). A histological diagnosis was always obtained. Main diagnoses included 15 germinal tumors (13 teratomas), 4 glial tumors, 2 craniopharyngiomas and 3 hamartomas. Average gestational age at diagnosis was 27 weeks for teratomas, 21 weeks for hamartomas and 34 weeks for glial tumors. All tumors but one were supra tentorial, and the lesion extended in the posterior fossa in two teratomas. A heterogeneous pattern, which was more frequently seen in teratomas, was better visualized by MR than US imaging. In addition, in two cases of teratomas, MR imaging better assessed the extension of the tumor. Teratomas and gliomas are the most frequent brain tumors in the fetus. US and MR imagings appear complementary in the prenatal assessment of these lesions.
胎儿颅内肿瘤较为罕见。诊断通常在出生后通过组织学检查做出。本研究的目的是分析一系列胎儿颅内肿瘤的临床和影像学数据，并强调可能有助于产前诊断的发现。我们回顾性分析了27例经超声（27/27）和磁共振成像（24/27）评估的胎儿颅内肿瘤的影像学和临床发现。均获得了组织学诊断。主要诊断包括15例生殖细胞肿瘤（13例畸胎瘤）、4例胶质瘤、2例颅咽管瘤和3例错构瘤。畸胎瘤诊断时的平均孕周为27周，错构瘤为21周，胶质瘤为34周。除1例肿瘤外，所有肿瘤均位于幕上，2例畸胎瘤的病变延伸至后颅窝。不均匀模式在畸胎瘤中更常见，磁共振成像比超声成像能更好地显示。此外，在2例畸胎瘤中，磁共振成像能更好地评估肿瘤的范围。畸胎瘤和胶质瘤是胎儿中最常见的脑肿瘤。超声和磁共振成像在这些病变的产前评估中似乎具有互补性。
