Maekawa Satoshi, Yoshikawa Ichiro, Yamasaki Masahiro, Kume Keiichiro, Kanda Kikuo, Kihara Yasuyuki, Tashiro Mitsuo, Otsuki Makoto
Third Department of Internal Medicine, Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine.
Nihon Shokakibyo Gakkai Zasshi. 2008 May;105(5):686-91.
A 62-year-old Japanese woman with ulcerative colitis (UC) had episcleritis and erythema nodosum. Oral administration of corticosteroid with granulocytapheresis improved all these diseases. Extraintestinal manifestations such as ocular and skin complications are infrequent, especially in Japan, in patients with UC. Although concurrent onset of episcleritis and erythema nodosum associated with UC is also extremely rare, clinical course in this case suggests a possible association among ulcerative colitis, episcleritis and erythema nodosum.
一名62岁患有溃疡性结肠炎(UC)的日本女性出现了巩膜外层炎和结节性红斑。口服皮质类固醇并进行粒细胞单采术使所有这些疾病都得到了改善。UC患者出现眼部和皮肤并发症等肠外表现并不常见,尤其是在日本。虽然与UC相关的巩膜外层炎和结节性红斑同时发作也极为罕见,但该病例的临床过程提示溃疡性结肠炎、巩膜外层炎和结节性红斑之间可能存在关联。