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[创伤性胸主动脉破裂:临床前评估、诊断及治疗选择]

[Traumatic thoracic aorta rupture: preclinical assessment, diagnosis and treatment options].

作者信息

Kopp R, Andrassy J, Czerner S, Weidenhagen A, Weidenhagen R, Meimarakis G, Reiser M, Jauch K W

机构信息

Chirurgische Klinik und Poliklinik, Klinikum der LMU München - Grosshadern, Marchioninistr. 15, 81377, München, Deutschland.

出版信息

Anaesthesist. 2008 Aug;57(8):782-93. doi: 10.1007/s00101-008-1375-1.

Abstract

Traumatic aortic rupture is a life-threatening injury which is frequently associated with blunt thoracic trauma or found coincidentally in heavily traumatized patients. Depending on the degree of disruption of the damaged aortic wall, vascular injury is associated with a high primary mortality rate and a significant risk of secondary aortic rupture. Early clinical signs which may indicate a ruptured thoracic aorta are left sided thoracic pain, reduced ventilation, tachycardia and dyspnoe as well as hypotension in the lower extremities. The primary aim for emergency treatment is to maintain vital organ function and to hemodynamically stabilize the patient. Surgical treatment was previously performed by either direct aortic suture or segmental alloplastic graft interposition using the clamp and sew technique with or without extra-anatomic shunts or extracorporeal circulation. However, endovascular stent graft implantation has now become another treatment option for traumatic aortic rupture. According to the reported data and our own experience there is increasing evidence that endovascular aortic repair might become the treatment of choice for patients with traumatic aortic rupture, with the option of an early, less invasive intervention thus avoiding thoracotomy. Regular follow-up is necessary to detect possible stent graft migration or leakage which could require additional endovascular or open surgical re-interventions.

摘要

创伤性主动脉破裂是一种危及生命的损伤,常与钝性胸部创伤相关,或在严重创伤患者中偶然发现。根据受损主动脉壁的破坏程度,血管损伤与高原发性死亡率和继发性主动脉破裂的显著风险相关。可能提示胸主动脉破裂的早期临床体征包括左侧胸痛、通气减少、心动过速、呼吸困难以及下肢低血压。紧急治疗的主要目标是维持重要器官功能并使患者血流动力学稳定。以前手术治疗是通过直接主动脉缝合或使用钳夹缝合技术进行节段性同种异体移植物植入,有无解剖外分流或体外循环。然而,血管内支架移植物植入现在已成为创伤性主动脉破裂的另一种治疗选择。根据报告的数据和我们自己的经验,越来越多的证据表明血管内主动脉修复可能成为创伤性主动脉破裂患者的首选治疗方法,可选择早期、侵入性较小的干预措施,从而避免开胸手术。定期随访对于检测可能需要额外血管内或开放手术再次干预的支架移植物迁移或渗漏是必要的。

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