Rousseau H, Dambrin C, Marcheix B, Richeux L, Mazerolles M, Cron C, Watkinson A, Mugniot A, Soula P, Chabbert V, Canevet G, Roux D, Massabuau P, Meites G, Tran Van T, Otal P
Department of Radiology, University Hospital Rangueil, 01 av. J Poulhes, 31403 Toulouse, France.
J Thorac Cardiovasc Surg. 2005 May;129(5):1050-5. doi: 10.1016/j.jtcvs.2004.12.023.
The study's objective was to comparatively evaluate surgery and stent-graft repair of acute or subacute traumatic aortic rupture.
A total of 76 patients (14-76 years old; mean, 37 years; male/female ratio, 63/11) with a traumatic aortic injury were admitted to our hospital between 1981 and 2003. Six patients died within 1 to 9 days of another associated severe traumatic lesion. The 70 remaining patients were divided according to the type of rupture repair. In group 1, 35 patients were treated surgically: 28 with immediate repair and 7 with delayed repair (average time interval 66 days, 5-257 days). In group 2, 29 patients were treated with stent grafting of the aortic isthmus. In group 3, 6 patients with minor aortic lesions were treated medically with a close follow-up.
In the 28 patients treated surgically in the emergency department, the mortality and paraplegia rates were 21% and 7%, respectively. No death or paraplegia was observed in the group with delayed surgical repair. With stent grafting, complete exclusion of the pseudoaneurysmal sac was observed in all patients. Except for 1 iliac rupture treated during the same procedure, there was no major morbidity or mortality during the mean follow-up of 46 months (13-90 months). No major complication was observed in group 3.
In stable rupture of the aorta, initial conservative treatment is safe and allows management of the major associated lesions. Stent grafting of the aortic isthmus is a valuable therapeutic alternative to surgical repair, especially in patients considered high risk for conventional thoracotomy.
本研究的目的是比较评估急性或亚急性创伤性主动脉破裂的手术治疗和支架移植物修复术。
1981年至2003年间,共有76例(年龄14 - 76岁;平均37岁;男女比例为63/11)创伤性主动脉损伤患者入住我院。6例患者因另一种相关的严重创伤性病变在1至9天内死亡。其余70例患者根据破裂修复类型进行分组。第1组,35例患者接受手术治疗:28例立即修复,7例延迟修复(平均时间间隔66天,5 - 257天)。第2组,29例患者接受主动脉峡部支架植入术。第3组,6例主动脉轻度病变患者接受密切随访的保守治疗。
在急诊科接受手术治疗的28例患者中,死亡率和截瘫率分别为21%和7%。延迟手术修复组未观察到死亡或截瘫病例。采用支架植入术,所有患者均实现了假性动脉瘤囊的完全封堵。除1例在同一手术过程中治疗的髂动脉破裂外,在平均46个月(13 - 90个月)的随访期间未出现严重并发症或死亡。第3组未观察到严重并发症。
在主动脉稳定破裂时,初始保守治疗是安全的,并且可以处理主要相关病变。主动脉峡部支架植入术是手术修复的一种有价值的治疗替代方法,特别是对于被认为传统开胸手术风险较高的患者。