Friedemann M
Bundesinstitut für Risikobewertung, Berlin, BRD.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2008 Jun;51(6):664-74. doi: 10.1007/s00103-008-0543-4.
Under inadequate hygienic conditions, opportunistic bacteria may multiply in powdered infant formula (PIF) and cause severe, often fatal neonatal infections. Enterobacter sakazakii has obtained Public Health relevance causing neonatal meningitis (often fatal), bacteremia and necrotizing enterocolitis. At highest risk are neonates up to two months of age. The new genus designation Cronobacter spp. nov. has been proposed to replace Enterobacter sakazakii. Enterobacter sakazakii is relatively resistant to osmotic and dry stress and may survive in PIF more than 2 years. (Inter)national organisations (EFSA, FAO, WHO, ESPGHAN, DGKJ, OGKJ, ISO) published their opinions recently. Manufacturers can minimize the risk of contamination of PIF by continuously improving technologies and by microbiological surveillance. Institutional and private consumers may reduce the risk of infection by using appropriate hygienic procedures.
在卫生条件不足的情况下,机会致病菌可能在婴儿配方奶粉中繁殖,并引发严重的、通常致命的新生儿感染。阪崎肠杆菌已成为具有公共卫生意义的病原菌,可导致新生儿脑膜炎(通常致命)、菌血症和坏死性小肠结肠炎。两个月龄以下的新生儿风险最高。已提议用新的属名“克罗诺杆菌属”来取代阪崎肠杆菌。阪崎肠杆菌对渗透压和干燥胁迫具有相对抗性,可能在婴儿配方奶粉中存活两年以上。(国际)组织(欧洲食品安全局、联合国粮农组织、世界卫生组织、欧洲儿科胃肠病、肝病和营养学会、德国儿科协会、奥地利儿科协会、国际标准化组织)最近发表了他们的意见。制造商可以通过不断改进技术和进行微生物监测,将婴儿配方奶粉受污染的风险降至最低。机构和个人消费者可以通过采用适当的卫生程序来降低感染风险。