Moreno V P, García-Raso A, García-Bueno M J, Sánchez-Sánchez C, Meseguer E, Mata R, Llamas P
Fundacion Jimenez Diaz, 28040 Madrid, España.
Rev Neurol. 2008;46(10):593-8.
Cardiovascular diseases are one of the leading health problems in developed countries. This term covers conditions such as coronary vascular disease, cerebrovascular diseases and peripheral vascular disease. Ischaemic cerebrovascular disease accounts for 80% of all cerebrovascular diseases. From a clinical point of view it is interesting to distinguish between modifiable and non-modifiable vascular risk factors.
To analyse the prevalence of modifiable vascular risk factors and their different combinations in a case-control study on ischaemic cerebrovascular disease in the Spanish population, and also the differences in the distribution of the risk factors according to the type of stroke (TOAST classification), age and sex.
The study was conducted on 308 patients with ischaemic stroke who were paired by age (+/- 5 years) and sex, with 307 controls with no prior history of thrombosis. The statistical analysis was performed using the software application SAS v. 9.1.
The results suggest that the risk factors are subject to an adding effect, as well as pointing to the presence of a specific profile of these factors depending on the subtype of stroke that is developed.
The addition of cardiovascular risk factors is associated with an increased risk of vascular events. The distribution of the modifiable vascular risk factors differs according to the type of stroke and the patient's sex and age.
心血管疾病是发达国家主要的健康问题之一。该术语涵盖冠状动脉疾病、脑血管疾病和外周血管疾病等病症。缺血性脑血管疾病占所有脑血管疾病的80%。从临床角度来看，区分可改变和不可改变的血管危险因素很有意思。
在一项针对西班牙人群缺血性脑血管疾病的病例对照研究中，分析可改变血管危险因素的患病率及其不同组合，以及根据卒中类型（TOAST分类）、年龄和性别划分的危险因素分布差异。
该研究对308例缺血性卒中患者进行，这些患者按年龄（±5岁）和性别配对，与307例无血栓形成病史的对照者进行比较。使用SAS v. 9.1软件应用程序进行统计分析。
结果表明，危险因素存在相加效应，并且根据所发生卒中的亚型显示出这些因素的特定特征。
心血管危险因素的增加与血管事件风险的增加相关。可改变血管危险因素的分布因卒中类型、患者性别和年龄而异。
