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缺血性中风:巴基斯坦男性和女性患者中可改变风险因素的患病率。

Ischemic stroke: prevalence of modifiable risk factors in male and female patients in Pakistan.

作者信息

Khan N I, Naz L, Mushtaq S, Rukh L, Ali S, Hussain Z

机构信息

Department of Physiology, University of Karachi, Karachi 75270, Pakistan.

出版信息

Pak J Pharm Sci. 2009 Jan;22(1):62-7.

Abstract

Stroke is the commonest neurological cause of morbidity and mortality all over the world being the third leading cause of death. Estimation of stroke risks in population is not only helpful for healthcare providers but also important to identify persons at elevated risk and to select proper treatments in clinical trials. The aim of the present study was to identify the prevalence of common modifiable risk factors for ischemic stroke in Pakistan. Patients of either sex above the age of 25 yrs who were admitted to Neurology Ward or came to OPD in Jinnah Post Graduate Medical Centre were included in the study. Type of stroke was identified by brain CT scans or MRI and risk factors for stroke and other details were noted on a proforma. Out of 55 patients studied for present study, 78% were males and 22% were females. Most of them belonged to low socioeconomic status and almost 50% were having family history of stroke. Most of the patients had multiple risk factors which included: hypertension (65%), smoking (32%), diabetes mellitus (36.3%), dyslipidemia (32.7%), coronary artery disease (9%), obesity (18%), epilepsy (16.3%) and left ventricular hypertrophy (3.6%). On the basis of these findings, it can be concluded that hypertension, smoking, dyslipidemia and diabetes mellitus are major risk factors for stroke and might be considered as main targets for primary and secondary prevention of stroke.

摘要

中风是全球发病率和死亡率最常见的神经学病因,是第三大死因。评估人群中的中风风险不仅对医疗服务提供者有帮助,对于识别高危人群以及在临床试验中选择合适的治疗方法也很重要。本研究的目的是确定巴基斯坦缺血性中风常见可改变风险因素的患病率。纳入研究的对象为25岁以上入住金奈研究生医学中心神经科病房或前往门诊的患者,无论性别。通过脑部CT扫描或MRI确定中风类型,并在表格上记录中风风险因素及其他详细信息。在本研究的55例患者中,78%为男性,22%为女性。他们大多属于社会经济地位较低的人群,近50%有中风家族史。大多数患者有多种风险因素,包括:高血压(65%)、吸烟(32%)、糖尿病(36.3%)、血脂异常(32.7%)、冠状动脉疾病(9%)、肥胖(18%)、癫痫(16.3%)和左心室肥厚(3.6%)。基于这些发现,可以得出结论,高血压、吸烟、血脂异常和糖尿病是中风的主要风险因素,可能被视为中风一级和二级预防的主要目标。

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