Esposito S, Principi N
Institute of Pediatrics, University of Milan, Milan, Italy.
J Chemother. 2008 Apr;20(2):147-57. doi: 10.1179/joc.2008.20.2.147.
The importance of rhinosinusitis finally reached pediatricians' attention a few years ago, and it has now been demonstrated that it is medically important and has a considerable socioeconomic impact in childhood. These guidelines, which have been prepared with and approved by many Italian Scientific Societies, are based on the most recent findings in the fields of clinical symptoms, imaging and microbiology tests for the diagnosis of acute rhinosinusitis, and efficacy evidence concerning antibiotic treatment and non-antibiotic adjuvant treatment. A Pubmed search using the key words "sinusitis", "rhinosinusitis", "child" and "antibiotic treatment", and the limits "human studies" and "English language", led to the selection of more than 2,700 articles published between 1966 and 2007. These guidelines are based on the 125 that were considered truly relevant and reflect the most widely shared positions concerning the diagnosis and treatment of acute, subacute and recurrent rhinosinusitis in children.
鼻窦炎的重要性在几年前终于引起了儿科医生的关注,现已证明它在医学上具有重要意义,并且对儿童时期有着相当大的社会经济影响。这些指南由众多意大利科学学会共同编写并批准,基于临床症状、影像学以及急性鼻窦炎诊断的微生物学检测等领域的最新研究结果,还有关于抗生素治疗和非抗生素辅助治疗的疗效证据。使用关键词“鼻窦炎”“鼻旁窦炎”“儿童”和“抗生素治疗”,并限定为“人体研究”和“英语语言”在PubMed上进行检索,筛选出了1966年至2007年间发表的2700多篇文章。这些指南基于125篇被认为真正相关的文章,反映了关于儿童急性、亚急性和复发性鼻旁窦炎诊断和治疗的最广泛共识。