Schoeffler M, Wallet F, Robert M O, Tramoni G, Workineh S, Viale J P, Duperret S
Unité de réanimation chirurgicale, hospices civils de Lyon, hôpital de Croix-Rousse, université de Lyon, Grande rue de Croix-Rousse, 69004 Lyon, France.
Ann Fr Anesth Reanim. 2008 Apr;27(4):345-7. doi: 10.1016/j.annfar.2008.01.006.
Duchenne muscular dystrophy (DMD) is a neuromuscular disease characterized by a progressive skeletal muscular weakness. As the respiratory care of such patients has been dramatically improved during the past few years, the DMD associated cardiomyopathy is becoming a new concern. We report a clinical case of a Troponin I level increase with normal coronarography occurring after an acute episode of respiratory failure. This report suggests the sensitivity of cardiomyocytes to hypoxemia in DMD patients.
杜氏肌营养不良症(DMD)是一种神经肌肉疾病,其特征为进行性骨骼肌无力。在过去几年中,此类患者的呼吸护理有了显著改善,与DMD相关的心肌病正成为一个新的关注点。我们报告了一例在急性呼吸衰竭发作后肌钙蛋白I水平升高而冠状动脉造影正常的临床病例。本报告提示了DMD患者心肌细胞对低氧血症的敏感性。