动脉粥样硬化风险社区研究（ARIC研究）中代谢综合征与心血管疾病和糖尿病的风险
Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study.
作者信息
Ballantyne C M, Hoogeveen R C, McNeill A M, Heiss G, Schmidt M I, Duncan B B, Pankow J S
机构信息
Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
出版信息
Int J Obes (Lond). 2008 May;32 Suppl 2(Suppl 2):S21-4. doi: 10.1038/ijo.2008.31.
OBJECTIVE
The metabolic syndrome is associated with increased risk for cardiovascular disease and diabetes. Several analyses from the Atherosclerosis Risk in Communities (ARIC) study have been performed to examine the role of the metabolic syndrome and its components in predicting risk for cardiovascular disease and diabetes.
DESIGN AND SUBJECTS
The large, biracial, population-based ARIC study enrolled 15792 middle-aged Americans in four communities in the United States and has followed them for the development of cardiovascular disease and diabetes.
MEASUREMENTS
Outcome parameters included prevalence of the metabolic syndrome and its individual components, carotid intima-media thickness, incident coronary heart disease, incident ischemic stroke and incident diabetes.
RESULTS AND CONCLUSION
Several analyses from the ARIC study have shown that the metabolic syndrome, as well as individual metabolic syndrome components, is predictive of the prevalence and incidence of coronary heart disease, ischemic stroke, carotid artery disease and diabetes.
目的
代谢综合征与心血管疾病和糖尿病风险增加相关。社区动脉粥样硬化风险（ARIC）研究已进行了多项分析，以检验代谢综合征及其组成部分在预测心血管疾病和糖尿病风险中的作用。
设计与研究对象
大型、基于双种族人群的ARIC研究在美国四个社区招募了15792名中年美国人，并对他们进行随访，观察心血管疾病和糖尿病的发生情况。
测量指标
结果参数包括代谢综合征及其各个组成部分的患病率、颈动脉内膜中层厚度、冠心病发病率、缺血性中风发病率和糖尿病发病率。
结果与结论
ARIC研究的多项分析表明，代谢综合征以及代谢综合征的各个组成部分可预测冠心病、缺血性中风、颈动脉疾病和糖尿病的患病率和发病率。
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