碘化铟（I）催化α-甲基烯丙基硼酸酯对N-酰基腙的区域和非对映选择性形式α-加成反应。

Indium(i) iodide-catalyzed regio- and diastereoselective formal alpha-addition of an alpha-methylallylboronate to N-acylhydrazones.

作者信息

Kobayashi Shū, Konishi Hideyuki, Schneider Uwe

机构信息

Department of Chemistry, School of Science and Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

出版信息

Chem Commun (Camb). 2008 May 28(20):2313-5. doi: 10.1039/b802153h. Epub 2008 Apr 17.

DOI:10.1039/b802153h

PMID:18473054

Abstract

Indium(i) iodide was found to catalyze the formal alpha-addition of an alpha-methylallylboronate to various N-acylhydrazones, in the presence of an alcohol additive, to afford the corresponding anti-alpha-adducts with high regio- and diastereoselectivity in high yields.

摘要

发现在醇添加剂存在下，碘化铟（I）能催化α-甲基烯丙基硼酸酯与各种N-酰基腙的形式上的α-加成反应，以高收率得到具有高区域和非对映选择性的相应反式α-加合物。