使用铟（I）催化剂实现酰腙与频哪醇烯丙基硼酸酯的通用催化烯丙基化反应的开发。

Development of general catalytic allylation of acylhydrazones with pinacolyl allylboronate using an indium(I) catalyst.

作者信息

Schneider Uwe, Chen I-Hon, Kobayashi Shū

机构信息

Department of Chemistry, School of Science and Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan Science and Technology Agency, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

出版信息

Org Lett. 2008 Mar 6;10(5):737-40. doi: 10.1021/ol702756k. Epub 2008 Feb 7.

DOI:10.1021/ol702756k

PMID:18254633

Abstract

Catalytic allylation of various acylhydrazones using a group 13 metal reagent (boron) in combination with a group 13 metal catalyst in its low-oxidation state (indium) has been developed. This operationally simple carbon-carbon bond-forming reaction displays remarkable substrate scope and functional group tolerance.

摘要

已开发出使用第13族金属试剂（硼）与低氧化态的第13族金属催化剂（铟）组合，对各种酰腙进行催化烯丙基化反应。这种操作简单的碳-碳键形成反应展现出显著的底物范围和官能团耐受性。