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锁核酸功能化金纳米颗粒作为通过三链体形成检测双链DNA的探针。

LNA functionalized gold nanoparticles as probes for double stranded DNA through triplex formation.

作者信息

McKenzie Fiona, Faulds Karen, Graham Duncan

机构信息

Centre for Molecular Nanometrology, WestCHEM, Glasgow, UK.

出版信息

Chem Commun (Camb). 2008 May 28(20):2367-9. doi: 10.1039/b802163e. Epub 2008 Mar 20.

DOI:10.1039/b802163e
PMID:18473072
Abstract

Nanoparticle modified LNA probes have been used for colorimetric identification of double stranded DNA via parallel triplex formation, eliminating the need for prior denaturation of the target duplex.

摘要

纳米颗粒修饰的锁核酸探针已被用于通过平行三链体形成对比色法鉴定双链DNA，无需对目标双链体进行预先变性。

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