Dar Nasser Rashid, Raza Naeem, Zafar Omar, Awan Salahuddin
Department of Dermatology, Combined Military Hospital, Lahore.
J Coll Physicians Surg Pak. 2008 Apr;18(4):236-8.
Papulonecrotic tuberculids represent an immunological expression of an internal focus of tuberculosis in an individual with a moderate or high degree of immunity. It responds to anti-tuberculosis treatment and is characterized by an eruption of necrotizing papules occurring in symmetrical crops, particularly affecting the elbows, knees, buttocks and face. A case of papulonecrotic tuberculids associated with immune mediated unilateral uveitis is reported in which all investigations were negative for tuberculosis except a strongly positive tuberculin test. There was an excellent response to anti-tuberculosis treatment. The association of immune mediated uveitis with papulonecrotic tuberculids has not been described before.
丘疹坏死性结核疹是结核病内在病灶在具有中度或高度免疫力个体中的一种免疫表现。它对抗结核治疗有反应,其特征为坏死性丘疹成批对称出现,尤其累及肘部、膝部、臀部和面部。本文报告了一例与免疫介导的单侧葡萄膜炎相关的丘疹坏死性结核疹病例,除结核菌素试验呈强阳性外,所有结核病相关检查均为阴性。抗结核治疗取得了极佳疗效。免疫介导的葡萄膜炎与丘疹坏死性结核疹的关联此前未见报道。