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幽门狭窄:从回顾性分析到前瞻性临床试验——对手术结果的影响

Pyloric stenosis: from a retrospective analysis to a prospective clinical trial - the impact on surgical outcomes.

作者信息

St Peter Shawn D, Ostlie Daniel J

机构信息

The Children's Mercy Hospital, Kansas City, Missouri, USA.

出版信息

Curr Opin Pediatr. 2008 Jun;20(3):311-4. doi: 10.1097/MOP.0b013e3282ff0de9.

Abstract

PURPOSE OF REVIEW

Pyloric stenosis is the most common surgical condition of infants. The operative approach, however, is currently debated in the literature following the application of laparoscopic and circumumbilical techniques to facilitate the pyloromyotomy. In this review, we will examine the published data and critically evaluate the influence of prospective data in delineating truths and illuminating flaws of retrospective data on a controversial topic.

RECENT FINDINGS

Retrospective data are highly discordant on the influence an operative approach for pyloromyotomy has on operating time, time to goal feeds, length of stay and complications. Prospective randomized data demonstrate that when the postoperative management is controlled, the approach does not influence length of recovery in a clinically relevant manner. Prospective data also demonstrate that the operating time can be the same for the laparoscopic and open approaches with no differences in complications for centers with good laparoscopic volume. There are no prospective data to contrast the circumumbilical approach with the other approaches; however there is an inherent and obvious cosmetic advantage to the laparoscopic and circumumbilical approaches, which avoid a large epigastric incision.

SUMMARY

The laparoscopic approach does not appear to influence length of recovery compared to the open operation. Prospective data show the laparoscopic approach results in less postoperative pain and can be done with no increase in operating time or complications.

摘要

综述目的

幽门狭窄是婴儿最常见的外科疾病。然而,随着腹腔镜和脐周技术应用于幽门肌切开术,目前文献中对手术方法存在争议。在本综述中,我们将研究已发表的数据,并批判性地评估前瞻性数据在阐明争议性话题真相和揭示回顾性数据缺陷方面的影响。

最新发现

回顾性数据在幽门肌切开术的手术方法对手术时间、达到目标喂养时间、住院时间和并发症的影响方面存在高度不一致。前瞻性随机数据表明,当术后管理得到控制时,手术方法不会以临床相关方式影响恢复时间。前瞻性数据还表明,对于腹腔镜手术量充足的中心,腹腔镜手术和开放手术的手术时间可以相同,并发症也无差异。没有前瞻性数据将脐周手术方法与其他方法进行对比;然而,腹腔镜和脐周手术方法具有内在且明显的美容优势,可避免上腹部大切口。

总结

与开放手术相比,腹腔镜手术似乎不影响恢复时间。前瞻性数据表明,腹腔镜手术术后疼痛较轻,且手术时间和并发症不会增加。

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