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[体外膜肺氧合在冠状动脉疾病外科治疗中的应用]

[The application of extracorporeal membrane oxygenation for surgical treatment of coronary artery disease].

作者信息

Yan Xiao-Lei, Li Qun, Yu Yang, Hou Xiao-Tong, Yang Yong, Wan Jiu-He, Jia Ming, Meng Xu, Jia Shi-Jie

机构信息

Intensive Care Unit, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2007 Dec 15;45(24):1714-6.

PMID:18476533
Abstract

OBJECTIVE

To summarize the results and experiences on extracorporeal membrane oxygenation (ECMO) for post-cardiac surgery of coronary artery disease.

METHODS

From June 2004 to November 2006, sixteen patients with the mean age of (58 +/- 11) years old undergoing cardiac surgical procedures were placed on ECMO using a heparin-bonded circuit. Fourteen patients were male and two patients were female. Thirteen patients underwent on pump coronary artery bypass surgery (CABG) and three patients underwent off-pump coronary artery bypass grafting. The duration of ECMO support, stay of intensive care unit (ICU stay), complications and turnovers were recorded.

RESULTS

The mean duration of ECMO support was 51 hours, and the mean duration of ICU stay was 5 days. Thirteen patients (81.3%) were successfully weaned form ECMO, ten patients (62.5%) were discharged from hospital. The main complications were bleeding, infection, renal failure and ischemia of the lower limbs with the incidence of 18.8%, 37.5%, 25% and 18.8% respectively.

CONCLUSION

ECMO is an acceptable technique for shortterm treatment of refractory low cardiac output after cardiac surgery of coronary artery disease.

摘要

目的

总结冠状动脉疾病心脏手术后体外膜肺氧合(ECMO)的结果及经验。

方法

2004年6月至2006年11月,16例平均年龄为(58±11)岁的患者在接受心脏手术时使用肝素涂层回路进行ECMO支持。其中男性14例,女性2例。13例行体外循环冠状动脉旁路移植术(CABG),3例行非体外循环冠状动脉旁路移植术。记录ECMO支持时间、重症监护病房(ICU)住院时间、并发症及转归情况。

结果

ECMO平均支持时间为51小时,ICU平均住院时间为5天。13例(81.3%)成功脱离ECMO,10例(62.5%)出院。主要并发症为出血、感染、肾衰竭及下肢缺血,发生率分别为18.8%、37.5%、25%和18.8%。

结论

ECMO是冠状动脉疾病心脏手术后难治性低心排血量短期治疗的一种可接受的技术。

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[The application of extracorporeal membrane oxygenation for surgical treatment of coronary artery disease].[体外膜肺氧合在冠状动脉疾病外科治疗中的应用]
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