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纵向数据广义部分线性混合模型中的稳健化最大似然估计

Robustified maximum likelihood estimation in generalized partial linear mixed model for longitudinal data.

作者信息

Qin Guo You, Zhu Zhong Yi

机构信息

Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China.

出版信息

Biometrics. 2009 Mar;65(1):52-9. doi: 10.1111/j.1541-0420.2008.01050.x. Epub 2009 Jun 5.

Abstract

In this article, we study the robust estimation of both mean and variance components in generalized partial linear mixed models based on the construction of robustified likelihood function. Under some regularity conditions, the asymptotic properties of the proposed robust estimators are shown. Some simulations are carried out to investigate the performance of the proposed robust estimators. Just as expected, the proposed robust estimators perform better than those resulting from robust estimating equations involving conditional expectation like Sinha (2004, Journal of the American Statistical Association99, 451-460) and Qin and Zhu (2007, Journal of Multivariate Analysis98, 1658-1683). In the end, the proposed robust method is illustrated by the analysis of a real data set.

摘要

在本文中,我们基于稳健似然函数的构建,研究广义部分线性混合模型中均值和方差分量的稳健估计。在一些正则条件下,给出了所提稳健估计量的渐近性质。进行了一些模拟以研究所提稳健估计量的性能。正如预期的那样,所提稳健估计量比那些由涉及条件期望的稳健估计方程(如Sinha(2004年,《美国统计协会杂志》99卷,451 - 460页)和Qin与Zhu(2007年,《多元分析杂志》98卷,1658 - 1683页))得到的估计量表现更好。最后,通过对一个真实数据集的分析来说明所提的稳健方法。

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