Xuan Xujun, Wang Daohu, Sun Peng, Mei Hua
Division of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Urol Int. 2008;80(3):321-4. doi: 10.1159/000127350. Epub 2008 May 14.
To assess the role of color Doppler flow imaging (CDFI) in the evaluation of Chinese patients with erectile dysfunction (ED) and to explore the association between penile rigidity and hemodynamic parameters of CDFI.
Totally 74 ED patients with an age range of 22-69 (median age 47) were included in our study, hemodynamic parameters including the peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistance index (RI) of the penile cavernous artery were measured by CDFI before and after intracavernous pharmacological testing. The degree of penile rigidity was classified according to Schramek grading system. The correlation between the penile rigidity state and its hemodynamic parameters was analyzed.
In ED patients, the abnormalities of cavernous artery and dorsal vein could be evaluated by the value of PSV and EDV with combination of penile rigidity. Among different penile rigidity status, the PSV, EDV and RI of the cavernous artery were significantly different (p < 0.05). The RI correlated significantly with the penile rigidity (r(2) = 0.7948).
The CDFI hemodynamics of the penile cavernous artery are helpful in the etiological diagnosis of Chinese ED patients and can be used as one of the quantitative indexes for penile rigidity, which is consistent with western guidelines.
评估彩色多普勒血流成像（CDFI）在中国勃起功能障碍（ED）患者评估中的作用，并探讨阴茎硬度与CDFI血流动力学参数之间的关联。
本研究纳入了74例年龄在22 - 69岁（中位年龄47岁）的ED患者，在海绵体内药物试验前后，通过CDFI测量阴茎海绵体动脉的血流动力学参数，包括收缩期峰值流速（PSV）、舒张末期流速（EDV）和阻力指数（RI）。根据施拉梅克分级系统对阴茎硬度进行分类。分析阴茎硬度状态与其血流动力学参数之间的相关性。
在ED患者中，结合阴茎硬度，通过PSV和EDV的值可评估海绵体动脉和背静脉的异常情况。在不同阴茎硬度状态下，海绵体动脉的PSV、EDV和RI有显著差异（p < 0.05）。RI与阴茎硬度显著相关（r(2) = 0.7948）。
阴茎海绵体动脉的CDFI血流动力学有助于中国ED患者的病因诊断，并可作为阴茎硬度的定量指标之一，这与西方指南一致。
