Department of Urology, Yangming Branch of Taipei City Hospital, Taipei, Taiwan.
J Sex Med. 2010 Dec;7(12):3979-83. doi: 10.1111/j.1743-6109.2009.01583.x.
Penile color Doppler ultrasonography (CDUS) with pharmacotesting has become an important tool for evaluating vascular erectile dysfunction (ED), and audio-visual sexual stimulation (AVSS) has been suggested to be helpful in assisting the performance of CDUS during the examination.
To investigate the feasibility of using a novel, remotely controllable AVSS system to assist CDUS.
This prospective randomized cross-over study recruited 60 consecutive ED patients. Each patient received three randomized sessions of CDUS under different conditions-AVSS, intracavernous injection (ICI) of alprostadil 20 microgram, or AVSS plus ICI. Clinical responses (rigidity) and penile vascular parameters including peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index (RI) were measured. At the end of the study, patients were asked about how they perceived the AVSS system in generating sexual arousal.
PSV, EDV, RI, and rigidity.
Fifty-eight ED patients (aged 21-79) underwent 174 sessions of CDUS. The mean PSV and maximal rigidity of patients under ICI alone were significantly greater than those of patients under AVSS alone (48.25 ± 22.78 vs. 36.54 ± 23.25 cm/second and 65.00 ± 23.93% vs. 43.28 ± 31.79%, respectively; both P < 0.05). The mean PSV of patients under AVSS plus ICI (55.38 ± 28.81 cm/second) was significantly greater than that of patients under ICI alone (P < 0.05), while the mean maximal rigidity (72.50 ± 22.03%) was only marginally greater (P = 0.082). EDV or RI was of no significant difference among the different conditions. Ultrasonographic diagnoses of ED under different conditions varied substantially. Fifty-four (93%) patients considered the AVSS system "very satisfactory" or "satisfactory" in evoking sexual arousal.
The novel, remotely controllable AVSS system is well accepted by patients and, in conjunction with ICI, helps to produce higher PSV for patients undergoing CDUS.
阴茎彩色多谱勒超声检查(CDUS)结合药物刺激已成为评估血管性勃起功能障碍(ED)的重要工具,视听性性刺激(AVSS)已被建议有助于在检查过程中辅助 CDUS 的进行。
探讨一种新型、远程可控的 AVSS 系统辅助 CDUS 的可行性。
这项前瞻性随机交叉研究招募了 60 名连续的 ED 患者。每位患者在三种不同条件下接受了三次随机的 CDUS 检查,分别为 AVSS、20 微克前列地尔的阴茎海绵体内注射(ICI)和 AVSS 加 ICI。测量了临床反应(硬度)和阴茎血管参数,包括收缩期峰值速度(PSV)、舒张末期速度(EDV)和阻力指数(RI)。研究结束时,询问患者对产生性唤起的 AVSS 系统的看法。
PSV、EDV、RI 和硬度。
58 名 ED 患者(年龄 21-79 岁)接受了 174 次 CDUS 检查。ICI 单独治疗组的平均 PSV 和最大硬度明显大于 AVSS 单独治疗组(48.25 ± 22.78 比 36.54 ± 23.25cm/秒和 65.00 ± 23.93%比 43.28 ± 31.79%;均 P < 0.05)。AVSS 加 ICI 组的平均 PSV(55.38 ± 28.81cm/秒)明显大于 ICI 单独治疗组(P < 0.05),而最大硬度的平均值(72.50 ± 22.03%)仅略有增加(P = 0.082)。不同条件下的 EDV 或 RI 无显著差异。不同条件下的 ED 超声诊断差异很大。54 名(93%)患者认为 AVSS 系统在唤起性唤起方面“非常满意”或“满意”。
新型、远程可控的 AVSS 系统得到了患者的广泛认可,并与 ICI 结合使用,有助于提高接受 CDUS 检查的患者的 PSV。