Narra Sri Lakshmi, Tombazzi Claudio, Datta Vivekanand, Ismail Mohammad K
Division of Gastroenterogy, Department of Medicine, University of Tennessee, Memphis, Tennessee 38103, USA.
Am J Med Sci. 2008 May;335(5):338-41. doi: 10.1097/MAJ.0b013e3181568197.
Granular cell tumor (GCT) is an uncommon esophageal neoplasm. It commonly presents as a nonspecific painless mass. The purpose of this study is to describe our experience with 5 patients newly diagnosed with GCT at VA Medical Center in Memphis, Tennessee from February 2001 to June 2005. Clinical manifestation, endoscopic appearance, histology, different modalities of treatment and prognosis are discussed. Based on this experience, we conclude that GCTs are relatively rare in occurrence. They usually present as a firm to hard submucosal nodule on esophagogastroduodenoscopy. Diagnosis can be made by endoscopic biopsy in most cases. Treatment options include endoscopic surveillance, endoscopic resection, or surgery. The usual course of GCTs is benign.
颗粒细胞瘤（GCT）是一种罕见的食管肿瘤。它通常表现为非特异性无痛肿块。本研究的目的是描述2001年2月至2005年6月期间我们在田纳西州孟菲斯市退伍军人医疗中心对5例新诊断为颗粒细胞瘤患者的治疗经验。讨论了临床表现、内镜表现、组织学、不同治疗方式及预后。基于这一经验，我们得出结论，颗粒细胞瘤的发病率相对较低。它们在食管胃十二指肠镜检查中通常表现为坚硬的黏膜下结节。大多数情况下可通过内镜活检进行诊断。治疗选择包括内镜监测、内镜切除或手术。颗粒细胞瘤的通常病程是良性的。
