肠道病毒脑膜炎婴儿脑脊液中的病毒载量
Viral loads of cerebrospinal fluid in infants with enterovirus meningitis.
作者信息
Kawashima Hisashi, Ioi Hiroaki, Ishii Chiako, Hasegawa Yuka, Amaha Masahiro, Kashiwagi Yasuyo, Takekuma Kouji, Hoshika Akinori, Watanabe Yasuo
机构信息
Department of Paediatrics, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, Japan.
出版信息
J Clin Lab Anal. 2008;22(3):216-9. doi: 10.1002/jcla.20244.
Abstract
For a better understanding of the role of the viral load, free radicals, and cytokines in viral meningitis, we surveyed cerebrospinal fluid (CSF) obtained from patients below 1 year of age who showed positive for enterovirus. In their first examinations interleukin (IL)-6 and free radicals increased whereas pleocytosis was rarely observed. IL-6 decreased within the short period. Viral loads and free radicals increased simultaneously. IL-6 and free radicals of CSF are helpful for diagnosis and treatment of viral meningitis at an early stage.
摘要
为了更好地理解病毒载量、自由基和细胞因子在病毒性脑膜炎中的作用，我们对1岁以下肠道病毒检测呈阳性的患者的脑脊液（CSF）进行了调查。在他们的首次检查中，白细胞介素（IL）-6和自由基增加，而很少观察到细胞增多。IL-6在短时间内下降。病毒载量和自由基同时增加。脑脊液中的IL-6和自由基有助于病毒性脑膜炎的早期诊断和治疗。
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