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马蹄肾的存在并不影响经皮肾镜取石术的结果。

The presence of horseshoe kidney does not affect the outcome of percutaneous nephrolithotomy.

作者信息

Miller Nicole L, Matlaga Brian R, Handa Shelly E, Munch Larry C, Lingeman James E

机构信息

Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

出版信息

J Endourol. 2008 Jun;22(6):1219-25. doi: 10.1089/end.2008.0051.

Abstract

BACKGROUND AND PURPOSE

Large or complex calculi within a horseshoe kidney can present a challenge because many cases are associated with other aberrant anatomy. We performed a study to define the outcome of patients with a horseshoe kidney who were treated with percutaneous nephrolithotomy (PNL).

PATIENTS AND METHODS

From August 1999 to February 2007, 44 PNLs were performed in 35 patients for calculi within a horseshoe kidney. Mean age was 55.4 years. Parameters evaluated to assess the outcomes of PNL included presenting symptoms, stone burden, location of access, stone-free rate, need for secondary intervention, length of stay (LOS), complication rate, stone analysis, and metabolic data.

RESULTS

The average stone burden per kidney was 2.59 cm (range 1-6.2 cm). Single percutaneous access was used in 97.7%. Location of the access tract was upper pole (82.2%), interpolar (13.4%), and lower pole (4.4 %). Flexible nephroscopy was performed in all patients. The stone-free rate after primary PNL was 84.1%. Second-look nephroscopy was performed in five kidneys. Overall stone-free rate was 93.2%. Average LOS was 1.92 days (range 1-4 d). Overall complication rate was 14.3%. Stone analysis revealed predominantly calcium stones, and metabolic abnormalities were demonstrated in all patients with 24-hour urine studies.

CONCLUSIONS

PNL is the treatment of choice for large and/or complex stones. The presence of a horseshoe kidney does not affect the outcome of PNL. Upper pole access is usually preferred, and flexible nephroscopy is essential to maximize stone-free rates. SA and metabolic data support the premise that calculus formation is a metabolic event.

摘要

背景与目的

马蹄肾内的大结石或复杂结石会带来挑战,因为许多病例与其他异常解剖结构相关。我们开展了一项研究,以明确接受经皮肾镜取石术(PNL)治疗的马蹄肾患者的治疗结果。

患者与方法

1999年8月至2007年2月,对35例马蹄肾结石患者实施了44次经皮肾镜取石术。平均年龄为55.4岁。评估经皮肾镜取石术治疗结果的参数包括出现的症状、结石负荷、穿刺部位、结石清除率、二次干预需求、住院时间(LOS)、并发症发生率、结石分析及代谢数据。

结果

每侧肾脏的平均结石负荷为2.59厘米(范围1 - 6.2厘米)。97.7%的患者采用了单次经皮穿刺。穿刺通道位于上极的占82.2%,极间的占13.4%,下极的占4.4%。所有患者均进行了软性肾镜检查。首次经皮肾镜取石术后结石清除率为84.1%。对5个肾脏进行了二期肾镜检查。总体结石清除率为93.2%。平均住院时间为1.92天(范围1 - 4天)。总体并发症发生率为14.3%。结石分析显示主要为钙结石,24小时尿液检查显示所有患者均有代谢异常。

结论

经皮肾镜取石术是治疗大结石和/或复杂结石的首选方法。马蹄肾的存在并不影响经皮肾镜取石术的治疗结果。通常首选上极穿刺,软性肾镜检查对于最大化结石清除率至关重要。结石分析和代谢数据支持结石形成是一个代谢事件这一前提。

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