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马蹄肾肾结石经皮肾镜取石术:影响结石清除率的因素。

Percutaneous nephrolithotomy in horseshoe kidneys: factors affecting stone-free rate.

机构信息

Second Department of Urology, Athens Medical School, Sismanoglio Hospital, Athens, Greece.

出版信息

J Urol. 2011 Nov;186(5):1894-8. doi: 10.1016/j.juro.2011.06.056. Epub 2011 Sep 23.

Abstract

PURPOSE

We report a 2-center study of factors affecting the stone-free rate after percutaneous nephrolithotomy in horseshoe kidneys.

MATERIALS AND METHODS

The postoperative stone-free rate after percutaneous nephrolithotomy was evaluated in 47 male and 11 female patients with horseshoe kidneys. All data were collected prospectively. Patient and procedure related factors predicting the stone-free rate were analyzed by univariate and multivariate tests.

RESULTS

The mean ± SD stone burden was 7.62 ± 7.18 cm(2) (range 1 to 45) and the stone was larger than 10 cm(2) in 14 patients (24.1%). Complex stones and staghorn stones were present in 21 (36.2%) and 19 patients (32.7%), respectively. The overall stone-free rate was 65.5%. Complex stones (p = 0.01), stone burden greater than 5 cm(2) (p = 0.013), stone burden greater than 10 cm(2) (p = 0.012), multiple stones (p = 0.006) and staghorn stones (p <0.001) were related to adverse outcomes on univariate analysis. Logistic regression analysis revealed that staghorn calculi was the only factor that significantly predicted the stone-free rate (p = 0.002). A patient with staghorn calculi in the horseshoe kidney was 45 times more likely to have a lower stone-free rate after percutaneous nephrolithotomy than a patient without staghorn calculi in the horseshoe kidney.

CONCLUSIONS

Stone parameters are important when treating calculi in horseshoe kidneys. Staghorn calculi are associated with a lower stone-free rate after percutaneous nephrolithotomy.

摘要

目的

我们报告了一项关于影响马蹄肾结石经皮肾镜取石术后无石率的因素的 2 中心研究。

材料与方法

对 47 名男性和 11 名女性马蹄肾结石患者进行了经皮肾镜取石术后无石率评估。所有数据均前瞻性收集。通过单因素和多因素检验分析预测无石率的患者和手术相关因素。

结果

平均 ± SD 结石负荷为 7.62 ± 7.18cm²(范围 1 至 45),14 例患者(24.1%)结石大于 10cm²。21 例(36.2%)存在复杂结石,19 例(32.7%)存在鹿角形结石。总体无石率为 65.5%。复杂结石(p=0.01)、结石负荷大于 5cm²(p=0.013)、结石负荷大于 10cm²(p=0.012)、多发结石(p=0.006)和鹿角形结石(p<0.001)在单因素分析中与不良结局相关。Logistic 回归分析显示,鹿角形结石是唯一显著预测无石率的因素(p=0.002)。马蹄肾结石患者存在鹿角形结石时,经皮肾镜取石术后无石率较低的可能性是无鹿角形结石患者的 45 倍。

结论

结石参数在治疗马蹄肾结石时很重要。鹿角形结石与经皮肾镜取石术后无石率较低相关。

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