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常规软性输尿管镜用于肾结石合并低密度肾结石经皮肾镜取石术:一项前瞻性、随机研究。

Routine flexible nephroscopy for percutaneous nephrolithotomy for renal stones with low density: a prospective, randomized study.

机构信息

Department of Urology, Abant İzzet Baysal University Faculty of Medicine, Bolura, Turkey.

出版信息

J Urol. 2013 Jul;190(1):144-8. doi: 10.1016/j.juro.2013.01.009. Epub 2013 Jan 9.

Abstract

PURPOSE

We evaluated the usefulness of routine flexible nephroscopy during percutaneous nephrolithotomy.

MATERIALS AND METHODS

Patients diagnosed with kidney stones who were scheduled to undergo percutaneous nephrolithotomy between March 2011 and July 2012 were randomized into 2 groups. Group 1 underwent standard percutaneous nephrolithotomy using rigid nephroscopy. Group 2 underwent flexible nephroscopy, in addition to standard percutaneous nephrolithotomy and laser lithotripsy or basket catheter stone extraction, as needed. Surgery was performed subcostally and with minimal percutaneous access in group 2 to use the advantages of flexible nephroscopy. We compared the 2 groups in terms of preoperative stone characteristics and postoperative success criteria, including the stone-free rate, bleeding, number of access sites, etc.

RESULTS

The study included 61 males (76.3%) and 19 females (23.8%) with a mean ± SD age of 43.75 ± 12.4 years (range 19 to 74). There was no significant difference in stone size, HU density or stone location between the 2 groups. Comparison of perioperative and postoperative parameters revealed a higher stone-free rate (92.5% vs 70%), fewer access sites and a lower hematocrit decrease in group 2. The stone-free rate was higher in patients with stones with a density of less than 677.5 HU (100% in group 2 vs 64.7% in group 1).

CONCLUSIONS

Routine flexible nephroscopy during percutaneous nephrolithotomy was associated with a higher stone-free rate, fewer interventions and less bleeding, especially in patients with low HU density stones.

摘要

目的

评估经皮肾镜取石术中常规应用软性肾镜的效果。

材料与方法

2011 年 3 月至 2012 年 7 月,我们将拟行经皮肾镜取石术的肾结石患者随机分为两组。组 1 采用硬性肾镜行标准经皮肾镜取石术;组 2 采用软性肾镜,在标准经皮肾镜取石术和激光碎石术或篮筐导管取石术的基础上,必要时加用软性肾镜。组 2 采用肋缘下最小经皮通道,以发挥软性肾镜的优势。我们比较了两组患者的术前结石特征和术后成功标准,包括结石清除率、出血、穿刺部位数量等。

结果

研究共纳入 61 例男性(76.3%)和 19 例女性(23.8%),平均年龄为 43.75 ± 12.4 岁(19~74 岁)。两组患者的结石大小、HU 密度或结石位置无显著差异。围手术期和术后参数的比较显示,组 2 的结石清除率(92.5%比 70%)更高,穿刺部位更少,血细胞比容下降更少。结石密度低于 677.5 HU 的患者结石清除率更高(组 2 为 100%,组 1 为 64.7%)。

结论

经皮肾镜取石术中常规应用软性肾镜可提高结石清除率,减少干预次数和出血,尤其适用于 HU 密度较低的结石患者。

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