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健康青少年脑电图后头部优势节律的定量分析

Quantitative analysis of the EEG posterior-dominant rhythm in healthy adolescents.

作者信息

Marcuse L V, Schneider M, Mortati K A, Donnelly K M, Arnedo V, Grant A C

机构信息

New York University School of Medicine, Department of Neurology, 403 East 34th Street, Rivergate 4th Floor, New York, NY 10016, USA.

Department of Policy, Planning and Design, University of California Irvine, Irvine, CA, USA.

出版信息

Clin Neurophysiol. 2008 Aug;119(8):1778-1781. doi: 10.1016/j.clinph.2008.02.023. Epub 2008 May 16.

DOI:10.1016/j.clinph.2008.02.023
PMID:18486545
Abstract

OBJECTIVE

Pivotal studies of the normal EEG posterior-dominant rhythm (PDR) typically relied on visual inspection of a few seconds of EEG data from a relatively small number of subjects in each age category. We sought to analyze and characterize the PDR in a large cohort of healthy 15-year-olds, and to determine if PDR characteristics mature over the following year.

METHODS

Seventy-nine healthy 15-year-olds free of neurologic and psychiatric disease underwent a resting-awake EEG, which was repeated 1 year later. In each study, PDR frequency was determined with fast Fourier transform analysis of a continuous 2-min EEG segment. t-Tests were used to compare relevant variables.

RESULTS

From age 15 to 16 the mean PDR frequency increased from 9.9 to 10.0Hz, a small but statistically significant difference. The PDR frequency range at both ages was 8.9-11.0Hz, similar to values reported in prior studies on healthy young adults. There was no significant difference in PDR frequency between genders or hemispheres.

CONCLUSIONS

Maturation of the PDR is nearly complete at age 16. The frequency range of the PDR in healthy adolescents and adults is substantially narrower than the alpha band.

SIGNIFICANCE

Based on this and prior studies, a PDR frequency of less than 8.5 or greater than 11.5Hz should be considered abnormal in adolescents and adults.

摘要

目的

关于正常脑电图后头部优势节律(PDR)的关键研究通常依赖于对每个年龄组相对少量受试者的几秒钟脑电图数据进行目视检查。我们试图分析和描述一大群健康15岁青少年的PDR,并确定PDR特征在接下来的一年中是否会成熟。

方法

79名无神经和精神疾病的健康15岁青少年接受了静息清醒脑电图检查,并在1年后重复进行。在每项研究中,通过对连续2分钟脑电图片段进行快速傅里叶变换分析来确定PDR频率。使用t检验比较相关变量。

结果

从15岁到16岁,平均PDR频率从9.9Hz增加到10.0Hz,差异虽小但具有统计学意义。两个年龄组的PDR频率范围均为8.9 - 11.0Hz,与先前关于健康年轻人的研究报告值相似。性别或半球之间的PDR频率无显著差异。

结论

PDR的成熟在16岁时几乎完成。健康青少年和成年人的PDR频率范围比α波段窄得多。

意义

基于本研究及先前研究,青少年和成年人的PDR频率低于8.5Hz或高于11.5Hz应被视为异常。

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