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[胶囊内镜在小肠克罗恩病诊断中的作用]

[The role of capsule endoscopy in the diagnosis of small bowel Crohn's disease].

作者信息

Pák Péter, Kovács Márta, Pák Gábor

机构信息

Vaszary Kolos Kórház, II. Belgyógyászati Osztály, Esztergom.

出版信息

Orv Hetil. 2008 May 25;149(21):983-8. doi: 10.1556/OH.2008.28378.

Abstract

Historically, there have been several modalities available for diagnosing small bowel diseases, but - until recently - endoscopic examination of this part of the gastrointestinal tract was not possible. With its direct visualization of bowel mucosa, the 2002 premier of capsule endoscopy was a major break-through in gastroenterology. The most important indication of small bowel capsule endoscopy is Crohn's disease, it provides valuable diagnostic information in patients with suspected, proven and post-operative disease, too. Several clinical studies proved CE's superiority over other methods. Although young age was a contraindication initially, numerous studies have proved its safety and efficacy in pediatric patients. Complications of CE are rare, the main risk is capsule retention and consequent small bowel ileus which can be prevented by a previous trial examination with a digestible, biodegradable patency test-capsule.

摘要

从历史上看,有多种方法可用于诊断小肠疾病,但直到最近,对胃肠道这一部分进行内镜检查还是不可能的。2002年胶囊内镜首次亮相,它可以直接观察肠黏膜,这是胃肠病学领域的一项重大突破。小肠胶囊内镜最重要的适应证是克罗恩病,它也为疑似、确诊及术后的患者提供了有价值的诊断信息。多项临床研究证明了胶囊内镜相对于其他方法的优越性。虽然年轻最初被视为禁忌证,但大量研究已证实其在儿科患者中的安全性和有效性。胶囊内镜的并发症很少见,主要风险是胶囊滞留及随之而来的小肠梗阻,这可以通过先前使用可消化、可生物降解的通畅试验胶囊进行的试验检查来预防。

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