Greco Filippo, Barbagallo Maria Luisa, Chiodo Danilo Castellano, Guglielmino Rosanna, Sorge Giovanni
Department of Pediatrics, University of Catania, Catania, Italy.
J Child Neurol. 2008 Sep;23(9):1078-80. doi: 10.1177/0883073808315420. Epub 2008 May 16.
Human parvovirus B19 generally causes erythema infectiosum in childhood, but it can be associated with unusual findings, particularly in immunocompromised patients. This is a report about an immunocompetent 4-year-old female child affected with acute encephalitis by parvovirus B19, documented by polymerase chain reaction performed on cerebrospinal fluid, who was treated with intravenous immunoglobulins and dexamethasone and who developed a cerebellar syndrome with ataxia, dysmetria, and dysarthria. To the best of the authors' knowledge, this may be the first report of human parvovirus B19 encephalitis complicated by severe ataxia in childhood.
人细小病毒B19通常在儿童期引起传染性红斑，但它可能伴有不寻常的表现，尤其是在免疫功能低下的患者中。本文报告了一名4岁免疫功能正常的女童，经脑脊液聚合酶链反应证实感染了细小病毒B19并患有急性脑炎，接受了静脉注射免疫球蛋白和地塞米松治疗，随后出现了伴有共济失调、辨距不良和构音障碍的小脑综合征。据作者所知，这可能是首例儿童细小病毒B19脑炎并发严重共济失调的报告。
