Sharashidze N, Pagava Z, Saatashvili G, Kishmarcia T, Agladze R
Georgian Med News. 2008 Apr(157):53-5.
Present work was aimed to study QT dispersion changes during exercise and relation of it with LV myocardium mass in veteran elite athletes. 31 veteran athletes aged 30-50 years and 31 age-matched healthy controls were studied. In all of them QT dispersion (QTd) at rest and during exercise test was evaluated. LV mass by ultrasound method was measured.
at least 10 years of competitive sports activity and 5 years after active sports cessation, absence of cardiovascular diseases. Differences in QTd at rest and exercise peak among athletes and control groups weren't statistically significant p<0, 05. However, in part of athletes (19%) QTd increased at peak of exercise (marker of pathological hypertrophy), in contrast of controls. Athletes group was divided in two subgroups: athletes with increased QTd at exercise peak (group A) and without of it (gourd B). LV mass index in group A (142,1; SD -4,5; 95% CI 139.31-144.69) was significantly higher, than in control group (106,5; SD -5,56; 95% CI 104.52-107.48) P<0,05. LV mass correlated with QT dispersion changes during exercise in veteran athletes (r =0,87). In former athletes increased QT dispersion during exercise was associated with LV mass enhancement. It is suggested that these findings are caused by incomplete regression of athletic heart hypertrophy or residual hypertrophy and it may not be pure physiological phenomenon.
目前的研究旨在探讨资深精英运动员运动期间QT离散度的变化及其与左心室心肌质量的关系。研究对象为31名年龄在30 - 50岁的资深运动员和31名年龄匹配的健康对照者。对所有研究对象进行静息和运动试验期间的QT离散度(QTd)评估。采用超声法测量左心室质量。
至少10年的竞技体育活动经历且停止积极运动5年后,无心血管疾病。运动员组和对照组静息及运动峰值时的QTd差异无统计学意义(p<0.05)。然而,部分运动员(19%)运动峰值时QTd增加(病理性肥厚的标志),与对照组相反。运动员组分为两个亚组:运动峰值时QTd增加的运动员(A组)和未增加的(B组)。A组的左心室质量指数(142.1;标准差 - 4.5;95%置信区间139.31 - 144.69)显著高于对照组(106.5;标准差 - 5.56;95%置信区间104.52 - 107.48),P<0.05。资深运动员运动期间左心室质量与QT离散度变化相关(r = 0.87)。在退役运动员中,运动期间QT离散度增加与左心室质量增加有关。提示这些发现是由运动员心脏肥厚的不完全消退或残余肥厚引起的,可能并非单纯的生理现象。