Mihaljevic Biljana S, Jovanovic Maja D Perunicic, Jakovic Ljubomir R, Sretenovic Aleksandra M, Boskovic Darinka V
Institute of Hematology, Clinical Center of Serbia, 2 Koste Todorovica Str, 11000 Belgrade, Serbia.
Med Oncol. 2008;25(2):245-7. doi: 10.1007/s12032-007-9012-4. Epub 2007 Oct 12.
Uterine cervix is an uncommon site for the presentation of Hodgkin's lymphoma. We describe a 62-year-old woman who developed an unusual relapse of classical Hodgkin's lymphoma, a nodular sclerosis subtype, in the uterine cervix, with propagation to the vaginal wall. She relapsed 15 years after achieving a complete remission of Hodgkin's lymphoma, initially in clinical stage IVB. This late relapse of the Hodgkin's lymphoma was in the clinical stage IEB and the treatment was initiated according to ABVD regimen. After the second course, lethal outcome ensued due to progression of the renal failure, which ensued in the meantime, probably as an adverse effect of the previous therapy.
子宫颈是霍奇金淋巴瘤较少见的发病部位。我们描述了一名62岁女性,她出现了经典型霍奇金淋巴瘤(结节硬化亚型)在子宫颈的罕见复发,并蔓延至阴道壁。她在霍奇金淋巴瘤完全缓解15年后复发,最初处于临床IVB期。此次霍奇金淋巴瘤的晚期复发处于临床IEB期,治疗按照ABVD方案启动。在第二个疗程后,因同时出现的肾衰竭进展导致了致命后果,肾衰竭可能是先前治疗的不良反应。