Johnston C, Senekjian E K, Ratain M J, Talerman A
Department of Obstetrics and Gynecology, University of Chicago, Pritzker School of Medicine, Illinois 60637.
Gynecol Oncol. 1989 Dec;35(3):391-4. doi: 10.1016/0090-8258(89)90086-3.
A 22-year-old nulligravida presented with a stage IE/IIIB primary malignant lymphoma of the cervix which measured 8 cm in diameter. In order to preserve reproductive potential, a 12-week course of methotrexate with leucovorin rescue, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin was administered. One month later a 4-cm-diameter left parametrial mass was excised at laparotomy; no tumor was detected in the specimens obtained. Menses resumed after an additional 6 months. The patient was clinically disease-free at the 33-month follow-up.
一名22岁未孕女性，患有直径8厘米的宫颈原发性恶性淋巴瘤，分期为IE/IIIB期。为保留生育能力，给予了为期12周的甲氨蝶呤联合亚叶酸钙解救、多柔比星、环磷酰胺、长春新碱、泼尼松和博来霉素治疗。1个月后，剖腹探查切除了直径4厘米的左侧宫旁肿物；所取标本中未检测到肿瘤。又过了6个月月经恢复。在33个月的随访中，患者临床无疾病。
