Tweedle C D, Hatton G I
Brain Res Bull. 1976 Jan-Feb;1(1):103-21. doi: 10.1016/0361-9230(76)90054-x.
A quantitative ultrastructural investigation was undertaken to compare the nucleus circularis (NC) and supraoptic nucleus (SON) of the rat both under normal and water-deprived conditions. NC was found to have dramatically more of its cells and membrane surface involved in direct soma-somatic contact than the SON. Water deprivation, even for one day, brought about a significant increase in both percentage of cells and membrane surface in contact in both nuclei, apparently by the retraction of fine glial processes from between the somata. The normal NC was made up of only one ultrastructurally identifiable cell type. The normal NC had no cells showing expanded endoplasmic reticulum, although these were seen following 5 days (but not 1 day) of water deprivation. The normal SON did have 4.4% of its cells showing expanded endoplasmic reticulum. This percentage significantly increased following water deprivation. The vesicle population per area of cytoplasm was very similar between the two normal nuclei. One day of water deprivation brought about a significant increase in less than 800 A vesicles in NC but not the SON. Five days of water deprivation resulted in a significant decrease in the lysosomal population per unit area in both nuclei. Vesicle changes have been discussed in relation to the volume changes in the cells.
进行了一项定量超微结构研究，以比较正常和缺水条件下大鼠的圆形核（NC）和视上核（SON）。结果发现，与SON相比，NC中有更多的细胞和膜表面参与直接的体细胞-体细胞接触。即使缺水一天，两个核中发生接触的细胞百分比和膜表面都会显著增加，这显然是由于体细胞间的细小神经胶质突起缩回所致。正常的NC仅由一种超微结构可识别的细胞类型组成。正常的NC中没有细胞显示内质网扩张，尽管在缺水5天（而非1天）后可见这种情况。正常的SON中有4.4%的细胞显示内质网扩张。缺水后这一百分比显著增加。两个正常核之间每单位细胞质面积的囊泡数量非常相似。缺水一天导致NC中直径小于800埃的囊泡显著增加，但SON中没有。缺水五天导致两个核中每单位面积的溶酶体数量显著减少。已结合细胞体积变化对囊泡变化进行了讨论。
