Gerbl-Rieger S, Peters J, Kellermann J, Lottspeich F, Baumeister W
Max-Planck Institut für Biochemie, Martinsried bei München, Federal Republic of Germany.
J Bacteriol. 1991 Apr;173(7):2196-205. doi: 10.1128/jb.173.7.2196-2205.1991.
The DNA sequence of the gene which codes for the major outer membrane porin (Omp32) of Comamonas acidovorans has been determined. The structural gene encodes a precursor consisting of 351 amino acid residues with a signal peptide of 19 amino acid residues. Comparisons with amino acid sequences of outer membrane proteins and porins from several other members of the class Proteobacteria and of the Chlamydia trachomatis porin and the Neurospora crassa mitochondrial porin revealed a motif of eight regions of local homology. The results of this analysis are discussed with regard to common structural features of porins.
编码嗜酸丛毛单胞菌主要外膜孔蛋白(Omp32)的基因的DNA序列已被测定。该结构基因编码一个由351个氨基酸残基组成的前体,带有一个19个氨基酸残基的信号肽。将其与变形菌门其他几个成员的外膜蛋白和孔蛋白的氨基酸序列、沙眼衣原体孔蛋白以及粗糙脉孢菌线粒体孔蛋白进行比较,发现了八个局部同源区域的基序。针对孔蛋白的共同结构特征对该分析结果进行了讨论。