大肠杆菌主要外膜蛋白之间的氨基酸序列同源性。
Amino acid sequence homology among the major outer membrane proteins of Escherichia coli.
作者信息
Nikaido H, Wu H C
出版信息
Proc Natl Acad Sci U S A. 1984 Feb;81(4):1048-52. doi: 10.1073/pnas.81.4.1048.
Abstract
Analysis of amino acid sequences reported for the major outer membrane proteins of Escherichia coli, including the porins (OmpF, OmpC, and PhoE), the phage lambda receptor (LamB), and another protein (OmpA), revealed several regions of local homology that is statistically significant. The implications of this observation are discussed in relation to the evolutionary origins of these proteins, as well as to the mechanism of export of these proteins to the outer membrane.
摘要
对已报道的大肠杆菌主要外膜蛋白的氨基酸序列分析，包括孔蛋白（OmpF、OmpC和PhoE）、噬菌体λ受体（LamB）以及另一种蛋白（OmpA），揭示了几个具有统计学意义的局部同源区域。结合这些蛋白质的进化起源以及这些蛋白质向外膜转运的机制，对这一观察结果的意义进行了讨论。
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本文引用的文献
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Similar amino acid sequences: chance or common ancestry?相似的氨基酸序列：偶然因素还是共同祖先？
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Primary structure of major outer-membrane protein I (ompF protein, porin) of Escherichia coli B/r.大肠杆菌B/r主要外膜蛋白I（ompF蛋白，孔蛋白）的一级结构
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Primary structure of major outer membrane protein II (ompA protein) of Escherichia coli K-12.大肠杆菌K-12主要外膜蛋白II（ompA蛋白）的一级结构
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