Muhwezi Wilson Winstons, Agren Hans, Neema Stella, Maganda Albert Koma, Musisi Seggane
Department of Psychiatry, Faculty of Medicine, Makerere University, Kampala, Uganda.
Int J Soc Psychiatry. 2008 Mar;54(2):144-63. doi: 10.1177/0020764007083878.
The study compared life events experienced by depressed patients seen at primary healthcare (PHC) centres with those among healthy community controls.
Data was collected from 74 depressed patients and 64 unmatched controls from village locales of patients. Interview instruments included the depression module of the Mini International Neuropsychiatric Interview (MINI) and Interview for Recent Life Events (IRLE). Associations between type of respondent and demographic variables were examined. Statistical comparisons were done for the two groups on other variables.
Most depressed patients were single by marital status, lacked formal employment and had less post-primary education.They had experienced more life events; job changes, discomforting working hours, unfavourable working conditions, and job losses; personal health problems; loss of valuables; difficulties with intimate partners and family members' marital problems. Independent life events were more among depressed patients and clustered around work, health, bereavement and marriage. Most events reported by depressed patients had high negative impact ratings compared to controls.
Compared to healthy community controls, depressed patients reported more undesirable life events. The relationship between life events and depression implies that in PHC settings of poor countries, deploying mental health-oriented workers to manage life events may lessen escalation of distress.
本研究比较了在初级卫生保健（PHC）中心就诊的抑郁症患者与健康社区对照者所经历的生活事件。
收集了74例抑郁症患者和64例来自患者所在村庄地区的非匹配对照者的数据。访谈工具包括迷你国际神经精神访谈（MINI）的抑郁模块和近期生活事件访谈（IRLE）。研究了受访者类型与人口统计学变量之间的关联。对两组在其他变量上进行了统计比较。
大多数抑郁症患者婚姻状况为单身，没有正式工作，小学以上学历较少。他们经历了更多的生活事件；工作变动、工作时间不适、工作条件不利和失业；个人健康问题；贵重物品丢失；与亲密伴侣的问题以及家庭成员的婚姻问题。独立生活事件在抑郁症患者中更多，且集中在工作、健康、丧亲和婚姻方面。与对照组相比，抑郁症患者报告的大多数事件具有较高的负面影响评分。
与健康社区对照者相比，抑郁症患者报告了更多不良生活事件。生活事件与抑郁症之间的关系表明，在贫穷国家的初级卫生保健环境中，部署以心理健康为导向的工作人员来处理生活事件可能会减少痛苦的升级。
