非转移性妊娠滋养细胞肿瘤的单药化疗。使用三十年之后的21世纪展望。
Single-agent chemotherapy for nonmetastatic gestational trophoblastic neoplasia. Perspectives for the 21st century after three decades of use.
作者信息
Kohorn E I
机构信息
Department of Gynecology, Yale University School of Medicine, New Haven, Connecticut 06510.
出版信息
J Reprod Med. 1991 Jan;36(1):49-55.
PMID:1848901
Abstract
After 30 years of successful chemotherapy for nonmetastatic gestational trophoblastic neoplasia, methotrexate and actinomycin remain the most effective and widely used agents. Though cost effectiveness is a consideration, primary efficacy may be a more important factor in this curable malignant disease. The criteria used for diagnosing neoplasia and for making therapeutic decisions were evaluated critically.
摘要
在对非转移性妊娠滋养细胞肿瘤进行了30年的成功化疗后，甲氨蝶呤和放线菌素仍然是最有效且使用最广泛的药物。尽管成本效益是一个需要考虑的因素，但在这种可治愈的恶性疾病中，主要疗效可能是更重要的因素。对用于诊断肿瘤形成和做出治疗决策的标准进行了严格评估。
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