用葡萄糖酸奎尼丁治疗严重恶性疟原虫疟疾：美国疾病控制与预防中心药物服务部门停止使用胃肠外奎宁
Treatment of severe Plasmodium falciparum malaria with quinidine gluconate: discontinuation of parenteral quinine from CDC drug service.
出版信息
MMWR Morb Mortal Wkly Rep. 1991 Apr 12;40(14):240.
PMID:1848916
Abstract
CDC has recently reviewed data on the reported incidence in the United States of Plasmodium falciparum malaria and has evaluated information on the effective management of severe life-threatening infections. As a result of this review, CDC has concluded that the drug of choice in the United States for treatment of complicated P. falciparum infections is parenteral quinidine gluconate. Therefore, effective immediately, parenteral quinine dihydrochloride will no longer be available from the CDC Drug Service.
摘要
美国疾病控制与预防中心（CDC）最近审查了美国恶性疟原虫疟疾报告发病率的数据，并评估了严重危及生命感染的有效管理信息。经过此次审查，CDC得出结论，在美国治疗复杂恶性疟原虫感染的首选药物是肠胃外注射葡萄糖酸奎尼丁。因此，自即日起，美国疾病控制与预防中心药品服务处将不再提供肠胃外注射二盐酸奎宁。
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Treatment of severe Plasmodium falciparum malaria with quinidine gluconate: discontinuation of parenteral quinine from CDC drug service.用葡萄糖酸奎尼丁治疗严重恶性疟原虫疟疾：美国疾病控制与预防中心药物服务部门停止使用胃肠外奎宁
MMWR Morb Mortal Wkly Rep. 1991 Apr 12;40(14):240.
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Treatment of severe malaria in the United States with a continuous infusion of quinidine gluconate and exchange transfusion.在美国，采用葡萄糖酸奎尼丁持续输注和换血疗法治疗重症疟疾。
N Engl J Med. 1989 Jul 13;321(2):65-70. doi: 10.1056/NEJM198907133210201.
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Availability and use of parenteral quinidine gluconate for severe or complicated malaria.用于重症或复杂疟疾的肠胃外葡萄糖酸奎宁的可及性和使用情况。
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Intravenous quinidine gluconate in the treatment of severe Plasmodium falciparum infections.静脉注射葡萄糖酸奎尼丁治疗严重恶性疟原虫感染
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Ineffectiveness of continuous quinidine gluconate infusion in the treatment of severe chloroquine-resistant Plasmodium falciparum malaria.连续输注葡萄糖酸奎宁治疗严重氯喹耐药恶性疟原虫疟疾无效。
Drug Intell Clin Pharm. 1988 Nov;22(11):883-5. doi: 10.1177/106002808802201110.
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Intravenous quinidine for the treatment of severe falciparum malaria. Clinical and pharmacokinetic studies.静脉注射奎尼丁治疗严重恶性疟。临床及药代动力学研究。
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[The anti-arrhythmia drug quinidine as an alternative in the treatment of severe falciparum malaria].[抗心律失常药物奎尼丁作为重症恶性疟治疗的替代药物]
Schweiz Med Wochenschr. 1983 Feb 19;113(7):254-8.
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