Chan Fion S, Chu Kent-Man
Division of Upper Gastrointestinal Surgery, Department of Surgery, The University of Hong Kong, Hong Kong SAR.
Asian J Surg. 2008 Apr;31(2):96-9. doi: 10.1016/S1015-9584(08)60066-4.
This is a review on the current status of capsule endoscopy in the assessment of patients with gastrointestinal bleeding of obscure origin after initial negative upper endoscopy and colonoscopy. Relevant information was gathered from a Medline search of the English literature, previous review and original articles, references cited in papers, and by checking the latest issues of appropriate journals. Based on the available evidence, capsule endoscopy, if done early in the course of investigation, can identify a bleeding lesion and thus direct subsequent test or treatment in about 60% of patients. Consequently, resources can potentially be saved as unnecessary investigations, blood transfusions and hospital admissions can be minimized and early implementation of definite treatments will be possible. The best candidates for capsule endoscopy are those with ongoing overt obscure bleeding or occult obscure bleeding. Large prospective studies are necessary to assess the impact of capsule endoscopy on clinical outcome.
这是一篇关于胶囊内镜在初始上消化道内镜检查和结肠镜检查结果为阴性的不明原因胃肠道出血患者评估中的现状综述。通过对英文文献进行医学数据库检索、查阅既往综述和原始文章、论文中引用的参考文献以及查阅相关期刊的最新期号来收集相关信息。基于现有证据，若在检查过程早期进行胶囊内镜检查，约60%的患者中可识别出出血病变，从而指导后续检查或治疗。因此，可节省资源，因为不必要的检查、输血和住院可减至最少，且能尽早实施确定性治疗。胶囊内镜的最佳适用对象是那些有持续性显性不明原因出血或隐匿性不明原因出血的患者。有必要开展大型前瞻性研究以评估胶囊内镜对临床结局的影响。
