Faiman Beth, Bilotti Elizabeth, Mangan Patricia A, Rogers Kathryn
Cleveland Clinic Foundation, Ohio, USA.
Clin J Oncol Nurs. 2008 Jun;12(3 Suppl):53-63. doi: 10.1188/08.CJON.S1.53-62.
Steroids have been the foundation of multiple myeloma therapy for more than 30 years and continue to be prescribed as single agents and in combination with other antimyeloma drugs, including novel therapies. Steroids cause a wide range of side effects that affect almost every system of the body. Identification and prompt management of the toxicities contribute to the success of steroid-containing antimyeloma regimens. By following patients carefully and educating them and their caregivers, nurses can promote adherence to therapy and improve quality of life. The International Myeloma Foundation's Nurse Leadership Board developed this consensus statement for the management of steroid-associated side effects to be used by healthcare providers in any medical setting.
30多年来,类固醇一直是多发性骨髓瘤治疗的基础,目前仍被作为单一药物以及与包括新型疗法在内的其他抗骨髓瘤药物联合使用。类固醇会引发一系列广泛的副作用,几乎影响身体的每个系统。识别并及时处理这些毒性反应有助于含类固醇抗骨髓瘤治疗方案的成功实施。通过密切关注患者并对患者及其护理人员进行教育,护士可以促进患者坚持治疗并提高生活质量。国际骨髓瘤基金会护士领导委员会制定了这份关于类固醇相关副作用管理的共识声明,供任何医疗环境中的医疗服务提供者使用。