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支气管扩张症的外科治疗:早期及长期疗效

Surgical treatment of bronchiectasis: early and long-term results.

作者信息

Giovannetti Riccardo, Alifano Marco, Stefani Alessandro, Legras Antoine, Grigoroiu Madalina, Collet Jean-Yves, Magdelenat Pierre, Regnard Jean-François

机构信息

Departement of Thoracic Surgery, Hôtel Dieu University Hospital, Paris V University, Paris, France.

出版信息

Interact Cardiovasc Thorac Surg. 2008 Aug;7(4):609-12. doi: 10.1510/icvts.2007.163972. Epub 2008 May 19.

Abstract

Management of bronchiectasis remains controversial and information on long-term results of surgical treatment is poor. Clinical records of 45 patients, who underwent surgery for bronchiectasis in an 8-year period, were retrospectively reviewed. Bronchiectasis focus was isolated in 24 cases, associated with a limited homolateral or controlateral focus in 9 and 11, respectively; two patients had bilateral evident foci. Bronchiectasis was responsible for lobe destruction in 23 cases. All patients had symptoms: haemoptysis (n=7), recurrent pneumonia (n=7), persistent bronchorrea with recurrent infection (n=15), hemoptysis and recurrent infection (n=16). A total of 23 lobectomies, 11 lobectomies+segmentectomies, 2 bi-lobectomies, 9 segmentectomies and 1 pneumonectomy were carried out. There were no perioperative deaths; complications occurred in 5 patients (postoperative pneumonia in 2, prolonged air-leak, residual air-space and bronchial infection 1 each). Symptoms disappeared in 32 patients, 10 patients experienced a significant improvement. Exercise tolerance remained stable or improved in 33 and 2 cases, respectively, a slight impairment was observed in 9. Out of 32 evaluable patients 11 had an unchanged FEV(1), 15 had a limited FEV(1) lowering (<15%), and 9 had a more important functional loss. Surgical treatment of bronchiectasis obtains satisfactory long-term results, with acceptable morbidity rates.

摘要

支气管扩张症的治疗仍存在争议,关于手术治疗长期效果的信息也很匮乏。对45例在8年期间接受支气管扩张症手术患者的临床记录进行了回顾性分析。24例患者的支气管扩张灶为孤立性,分别有9例和11例伴有同侧或对侧局限性病灶;2例患者双侧有明显病灶。23例患者的支气管扩张导致肺叶毁损。所有患者均有症状:咯血(7例)、反复肺炎(7例)、持续性支气管溢液伴反复感染(15例)、咯血伴反复感染(16例)。共实施了23例肺叶切除术、11例肺叶切除术+肺段切除术、2例双侧肺叶切除术、9例肺段切除术和1例全肺切除术。无围手术期死亡;5例患者出现并发症(2例术后肺炎,1例持续性漏气、1例残留气腔和1例支气管感染)。32例患者症状消失,10例患者有显著改善。33例和2例患者的运动耐量分别保持稳定或改善,9例患者有轻微受损。在32例可评估患者中,11例患者第一秒用力呼气容积(FEV₁)无变化,15例患者FEV₁有轻度降低(<15%),9例患者有更严重的功能丧失。支气管扩张症的手术治疗可获得满意的长期效果,发病率可接受。

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