Etienne T, Spiliopoulos A, Megevand R
Département de Chirurgie, Hôpital Cantonal Universitaire, Genève, Suisse.
Ann Chir. 1993;47(8):729-35.
Despite continuous improvement in the medical treatment of bronchiectasis, a number of patients will eventually require surgery. The optimal timing of surgical resection and the efficacy of surgery need to be reassessed in this context. The records of 85 patients operated for bronchiectasis during the period 1971-1991 were reviewed. Six patients underwent repeated surgical resections. Long term results could be assessed in 73 patients (86%) by means of questionnaire or subsequent medical evaluation. Indications for surgery were: persistent symptoms under medical treatment in 43 cases (51%), local complications such as fungal superinfection or severe bleeding in 17 (20%) and 11 (13%) respectively, pulmonary mass lesions in 14 (16%). Limited resections such as segmentectomies or lobectomies were carried out in 79 cases (93%). In patients with localized disease (N = 49), surgery led to significant improvement in 91% of cases. In patients with extensive or complicated disease (N = 36), long term results of surgery were satisfactory in 62% and poor in 38%; surgery was often more aggressive in this group of patients (5 pneumonectomies), and 4 postoperative deaths occurred (in debilitated patients). Patients with localized disease and recurrent symptoms despite medical treatment should be operated before the development of complications. At this stage, surgical resection can be limited and has the potential to cure or significantly improve their condition. In contrast, patients with extensive disease are often debilitated and surgical treatment is less rewarding and sometimes poorly tolerated.
尽管支气管扩张症的医学治疗不断改进,但仍有一些患者最终需要手术治疗。在此背景下,手术切除的最佳时机和手术疗效需要重新评估。回顾了1971年至1991年期间85例因支气管扩张症接受手术的患者记录。6例患者接受了重复手术切除。通过问卷调查或后续医学评估,可对73例患者(86%)进行长期结果评估。手术指征为:43例(51%)在药物治疗下仍有持续症状;17例(20%)和11例(13%)分别出现局部并发症,如真菌二重感染或严重出血;14例(16%)有肺部肿块病变。79例(93%)进行了有限切除,如肺段切除术或肺叶切除术。对于局限性疾病患者(N = 49),手术使91%的病例得到显著改善。对于广泛性或复杂性疾病患者(N = 36),手术的长期结果在62%的病例中令人满意,38%的病例结果不佳;该组患者的手术往往更具侵袭性(5例全肺切除术),术后有4例死亡(均为身体虚弱的患者)。尽管接受了药物治疗,但仍有局限性疾病且症状复发的患者应在并发症出现之前进行手术。在此阶段,手术切除范围可有限,且有可能治愈或显著改善其病情。相比之下,广泛性疾病患者往往身体虚弱,手术治疗效果较差,有时耐受性也很差。