Okada Masahiro, Murakami Takamichi, Kumano Seishi, Imaoka Izumi, Shimono Taro, Ashikaga Ryuichiro, Hosono Makoto
Department of Radiology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan.
AJR Am J Roentgenol. 2008 Jun;190(6):W323-6. doi: 10.2214/AJR.07.3047.
The purpose of our study was to evaluate whether simultaneous injection into cubital veins bilaterally at one half of the standard injection rate achieves similar hepatic and aortic enhancement on MDCT as the conventional injection rate into a single cubital vein.
Thirty-two patients underwent multiphase MDCT because they were suspected of having a hepatic tumor. Patients were assigned to one of the following two groups: group A, 100 mL of 370 mg I/mL of contrast medium injected into a unilateral cubital vein (one-route) via a 20-gauge cannula at a rate of 4 mL/s; or group B, 50 mL of contrast medium injected into the cubital veins bilaterally (two-route) via 24-gauge cannulas at 2 mL/s. Peak contrast enhancement of the liver and abdominal aorta for groups A and B was measured using regions of interest and compared; arrival time of the contrast media was also compared using a bolus-tracking system. Analysis was performed using Wilcoxon's signed rank test.
Peak aortic enhancement of groups A and B was 367 +/- 67 H and 361 +/- 113 H (p = 0.61, not significant), respectively, and peak hepatic enhancement of groups A and B was 56 +/- 11 H and 56 +/- 16 H (p = 0.88, not significant), respectively. Mean arrival time to the aorta of group B (19.4 +/- 3.4 seconds) was significantly later compared with that of group A (15.5 +/- 3.5 seconds) (p = 0.005).
The slower two-route injection produced the same aortic and hepatic enhancement as the faster one-route method with faster injection, but the arrival time of the contrast medium was later using the two-route method.
本研究旨在评估以标准注射速率的一半同时双侧肘静脉注射，在多排螺旋CT（MDCT）上是否能产生与传统单肘静脉注射速率相似的肝脏和主动脉强化效果。
32例因怀疑患有肝脏肿瘤而接受多期MDCT检查的患者。患者被分为以下两组之一：A组，100 mL浓度为370 mg I/mL的造影剂经20号套管以4 mL/s的速率注入单侧肘静脉（单路）；或B组，50 mL造影剂经24号套管以2 mL/s的速率双侧注入肘静脉（双路）。使用感兴趣区测量并比较A组和B组肝脏和腹主动脉的峰值强化；还使用团注追踪系统比较造影剂的到达时间。采用Wilcoxon符号秩检验进行分析。
A组和B组主动脉峰值强化分别为367±67 H和361±113 H（p = 0.61，无显著性差异），A组和B组肝脏峰值强化分别为56±11 H和56±16 H（p = 0.88，无显著性差异）。B组到达主动脉的平均时间（19.4±3.4秒）明显晚于A组（15.5±3.5秒）（p = 0.005）。
较慢的双路注射与较快的单路注射方法产生相同的主动脉和肝脏强化效果，但双路注射法造影剂的到达时间较晚。
