Adam G, Brab M, Bohndorf K, Klose K C, Günther R W
Klinik für Radiologische Diagnostik der Rheinisch Westfälischen Technischen Hochschule Aachen.
Rofo. 1991 Mar;154(3):275-80. doi: 10.1055/s-2008-1033132.
Twenty-one patients with malignant melanoma of the uvea or iris, some with intra-ocular bleeding, were examined by MRT before and after the administration of Gd/DTPA. In 13 patients, several examinations were performed over a period of 1.5 to 20 months after irradiation of the melanoma. After Gd-DTPA there was an average increase of 13% in the signal intensity from all non-irradiated melanomas (17 cases). Three months following radiation therapy, there was an average increase in signal intensity after Gd-DTPA of 65.7%, and after seven months of 100%. Amelanotic melanomas (two cases) showed a primary increase in intensity of 100%. Two melanomas of the iris were demonstrated by sonography; of these, only one could be shown with certainty by MRT. Small tumours and tumour residues after irradiation were better defined after contrast. In the presence of suspected intra-ocular bleeding, the examination should always be performed after the administration of Gd-DTPA.
21例患有葡萄膜或虹膜恶性黑色素瘤的患者，部分伴有眼内出血，在给予钆喷酸葡胺（Gd/DTPA）前后接受了磁共振成像（MRT）检查。13例患者在黑色素瘤放疗后的1.5至20个月期间进行了多次检查。给予Gd-DTPA后，所有未接受放疗的黑色素瘤（17例）信号强度平均增加了13%。放疗三个月后，给予Gd-DTPA后信号强度平均增加65.7%，七个月后增加100%。无色素性黑色素瘤（2例）信号强度最初增加100%。超声检查显示了2例虹膜黑色素瘤；其中，磁共振成像仅能明确显示1例。放疗后的小肿瘤和肿瘤残留经造影后显示更清晰。在怀疑存在眼内出血的情况下，应始终在给予Gd-DTPA后进行检查。
