Doringer E, Joos H, Forstner R, Schmoller H
Röntgendiagnostisches Zentralinstitut der Landeskrankenanstalten, Salzburg.
Rofo. 1991 Apr;154(4):357-63. doi: 10.1055/s-2008-1033150.
33 patients with tumours of the urinary bladder were studied via MR, both with and without the paramagnetic contrast medium Gd-DTPA. Results were compared with the final pathological classification after TUER and bimanual palpation. The signal intensity ratio of tumour tissue/fat and tumour/muscle were calculated on T1 weighted images and after GD-DTPA and examined for their statistical significance. The increase in signal intensity of the tumours was statistically significant (Wilcoxon test p less than 0.01). There was no advantage for the T2 weighted images compared with Gd-contrasted enhanced T1 weighted images. MRI staging was correct in 28 out of 33 cases (accuracy 84.8%). Because of the relatively short acquisition time of T1 weighted images and the specific tumour enhancement, administration of Gd-DTPA proved to be of help in the staging of the carcinoma of the bladder. Two small tumours and regressive changes in central areas of tumours were recognised after Gd-DTPA.
对33例膀胱肿瘤患者进行了磁共振成像（MR）研究，分别在使用和顺磁性造影剂钆喷酸葡胺（Gd-DTPA）的情况下进行。将结果与经尿道电切术（TUER）和双合诊触诊后的最终病理分类进行比较。在T1加权图像上以及使用Gd-DTPA后，计算肿瘤组织/脂肪和肿瘤/肌肉的信号强度比，并检验其统计学意义。肿瘤信号强度的增加具有统计学意义（Wilcoxon检验，p<0.01）。与Gd增强的T1加权图像相比，T2加权图像并无优势。33例中有28例MRI分期正确（准确率84.8%）。由于T1加权图像的采集时间相对较短以及肿瘤的特异性强化，Gd-DTPA的应用被证明有助于膀胱癌的分期。使用Gd-DTPA后识别出两个小肿瘤以及肿瘤中心区域的退行性改变。
