一种用于染色体共定位的热力学开关。
A thermodynamic switch for chromosome colocalization.
作者信息
Nicodemi Mario, Panning Barbara, Prisco Antonella
机构信息
Department of Physics and Complexity Science, University of Warwick, Coventry CV4 7AL, United Kingdom.
出版信息
Genetics. 2008 May;179(1):717-21. doi: 10.1534/genetics.107.083154.
Abstract
A general model for the early recognition and colocalization of homologous DNA sequences is proposed. We show, on thermodynamic grounds, how the distance between two homologous DNA sequences is spontaneously regulated by the concentration and affinity of diffusible mediators binding them, which act as a switch between two phases corresponding to independence or colocalization of pairing regions.
摘要
提出了一种用于同源DNA序列早期识别和共定位的通用模型。我们基于热力学原理表明，两个同源DNA序列之间的距离如何通过结合它们的可扩散介质的浓度和亲和力自发调节，这些介质在对应于配对区域独立或共定位的两个相之间起开关作用。
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2
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Phys Rev Lett. 2007 Mar 9;98(10):108104. doi: 10.1103/PhysRevLett.98.108104. Epub 2007 Mar 7.
3
Beyond the sequence: cellular organization of genome function.超越序列：基因组功能的细胞组织
Cell. 2007 Feb 23;128(4):787-800. doi: 10.1016/j.cell.2007.01.028.
4
Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions.核空间中的动态基因组架构：三维空间中基因表达的调控
Nat Rev Genet. 2007 Feb;8(2):104-15. doi: 10.1038/nrg2041.
5
A family of zinc-finger proteins is required for chromosome-specific pairing and synapsis during meiosis in C. elegans.秀丽隐杆线虫减数分裂过程中，染色体特异性配对和联会需要一个锌指蛋白家族。
Dev Cell. 2006 Dec;11(6):817-29. doi: 10.1016/j.devcel.2006.09.020.
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From early homologue recognition to synaptonemal complex formation.从早期同源物识别到联会复合体形成。
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7
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