He Miao-Xia, Zhu Ming-Hua, Liu Wei-Qiang, Wu Li-Li, Zhu Xiong-Zeng
Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
World J Gastroenterol. 2008 May 21;14(19):3101-4. doi: 10.3748/wjg.14.3101.
Primary stomach lymphoblastic B-cell lymphoma (B-LBL) is a rare tumor. We describe a primary stomach B-LBL in a 38 years old female who presented with nonspecific complaints of fatigue and vomiting for 2 mo. Gastrofiberscopy revealed a large gastric ulcer, which was successfully resected. Pathology showed a lymphoblastic cell lymphoma arising from the stomach, and there was no evidence of disease at any extrastomach site. Immunohistochemical staining and gene rearrangement studies supported that the stomach tumor was a clonal B-cell lymphoma. Therefore, the diagnosis of B-LBL was made based on the stomach specimen.
原发性胃淋巴母细胞性B细胞淋巴瘤(B-LBL)是一种罕见肿瘤。我们描述了一名38岁女性的原发性胃B-LBL,她因疲劳和呕吐等非特异性症状就诊,症状持续2个月。胃镜检查发现一个大的胃溃疡,该溃疡被成功切除。病理显示为起源于胃的淋巴母细胞性淋巴瘤,且在任何胃外部位均无疾病证据。免疫组织化学染色和基因重排研究支持胃肿瘤为克隆性B细胞淋巴瘤。因此,根据胃标本做出了B-LBL的诊断。