Becker T M, Wheeler C M, McGough N S, Jordan S W, Dorin M, Miller J
Department of Medicine, School of Medicine, University of New Mexico, Albuquerque 87131.
Am J Public Health. 1991 May;81(5):582-6. doi: 10.2105/ajph.81.5.582.
Human papillomavirus infections of the cervix are found with varying frequencies in different populations worldwide, and have been associated with cervical cytologic abnormalities.
We studied 1,603 randomly selected Hispanic, Native American, and non-Hispanic White women in New Mexico to determine the prevalence of cervical HPV infection in these ethnic groups, and its association with Pap smear abnormalities, using a new commercial dot-blot hybridization assay.
Nine percent of all women screened had evidence of cervical HPV infection (13.7% of non-Hispanic White women, 9.7% of Hispanics, and 6.6% of Native American women). Prevalence was higher in younger women ages 14-19 years than in older age groups. Over half of women with cervical HPV infection (n = 145) had normal Pap smears. The proportion of infected women increased among those with more advanced cytopathologic abnormalities; 5.6 percent with normal Pap smears had cervical HPV vs 66.7 percent with moderate-severe dysplasia.
Cervical HPV infection is common among New Mexico clinic attendees, varies in prevalence among the three major ethnic groups, and is strongly associated with cervical cytopathologic abnormalities.
人乳头瘤病毒宫颈感染在全球不同人群中的发现频率各异，且与宫颈细胞学异常有关。
我们在新墨西哥州对1603名随机选取的西班牙裔、美洲原住民和非西班牙裔白人女性进行了研究，采用一种新的商业斑点杂交检测法来确定这些种族群体中宫颈人乳头瘤病毒感染的患病率及其与巴氏涂片异常的关联。
所有接受筛查的女性中有9%有宫颈人乳头瘤病毒感染的证据（非西班牙裔白人女性为13.7%，西班牙裔为9.7%，美洲原住民女性为6.6%）。14至19岁的年轻女性患病率高于其他年龄组。超过一半的宫颈人乳头瘤病毒感染女性（n = 145）巴氏涂片正常。在细胞病理学异常程度更严重的女性中，感染女性的比例增加；巴氏涂片正常的女性中有5.6%感染了宫颈人乳头瘤病毒，而中度至重度发育异常的女性中这一比例为66.7%。
宫颈人乳头瘤病毒感染在新墨西哥州就诊的人群中很常见，在三个主要种族群体中的患病率有所不同，并且与宫颈细胞病理学异常密切相关。
