Lisabeth Lynda D, Smith Melinda A, Sánchez Brisa N, Brown Devin L
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Am J Hypertens. 2008 Jul;21(7):778-83. doi: 10.1038/ajh.2008.161. Epub 2008 May 22.
Little data exist on stroke burden in Mexican-American (MA) women. The objective of this study was to characterize the burden of stroke in MA and non-Hispanic white (NHW) women and to compare this burden across ethnic groups.
Cases of ischemic stroke and intracerebral hemorrhage among women (January 2000-December 2006) were identified as part of the Brain Attack Surveillance in Corpus Christi (BASIC) Project, a stroke surveillance study in a biethnic Texas community. Cumulative incidence of stroke among women was compared by ethnicity and age. Logistic regression was used to compare risk factors and age-adjusted use of antihypertensives between MA and NHW female stroke cases.
MA women had elevated stroke risk compared with NHW women at younger ages (ages 45-59: relative risk (RR) = 2.00 (95% confidence interval (CI): 1.54-2.58); ages 60-74: RR = 1.57 (95% CI: 1.31-1.87); ages > or =75: RR = 1.13 (95% CI: 0.98-1.29)). Stroke severity and stroke type did not differ between ethnic groups. MA female stroke cases were more likely to have hypertension (odds ratio (OR) = 1.41 (95% CI: 1.11-1.80)), diabetes (OR = 3.54 (95% CI: 2.82-4.45)), and the presence of both risk factors (OR = 3.31 (95% CI: 2.61-4.21)) compared with NHW female stroke cases and were more likely to report use of antihypertensives (OR = 1.51 (95% CI: 1.10-2.06)). There was a trend toward greater hypertension awareness among MA female stroke cases (OR = 1.37 (95% CI: 0.98-1.91)).
MA women have increased risk of stroke at younger ages compared with NHW women. Reasons for this ethnic disparity, including an increased prevalence of hypertension and diabetes, should be explored.
关于墨西哥裔美国（MA）女性中风负担的数据很少。本研究的目的是描述MA和非西班牙裔白人（NHW）女性的中风负担，并比较不同种族群体之间的这种负担。
作为科珀斯克里斯蒂脑卒中新发情况监测（BASIC）项目的一部分，确定了2000年1月至2006年12月期间女性缺血性卒中和脑出血病例，该项目是对德克萨斯州一个双种族社区进行的中风监测研究。按种族和年龄比较女性中风的累积发病率。使用逻辑回归比较MA和NHW女性中风病例的危险因素以及年龄调整后的抗高血压药物使用情况。
与NHW女性相比，MA女性在较年轻年龄段（45 - 59岁：相对风险（RR）= 2.00（95%置信区间（CI）：1.54 - 2.58）；60 - 74岁：RR = 1.57（95% CI：1.31 - 1.87）；年龄≥75岁：RR = 1.13（95% CI：0.98 - 1.29））中风风险升高。种族群体之间中风严重程度和中风类型没有差异。与NHW女性中风病例相比，MA女性中风病例更有可能患有高血压（优势比（OR）= 1.41（95% CI：1.11 - 1.80））、糖尿病（OR = 3.54（95% CI：2.82 - 4.45））以及同时存在这两种危险因素（OR = 3.31（95% CI：2.61 - 4.21）），并且更有可能报告使用抗高血压药物（OR = 1.51（95% CI：1.10 - 2.06））。MA女性中风病例中有高血压知晓率更高的趋势（OR = 1.37（95% CI：0.98 - 1.91））。
与NHW女性相比，MA女性在较年轻年龄段中风风险增加。应探究这种种族差异的原因，包括高血压和糖尿病患病率的增加。
